{"id":"W2332286919","doi":"10.1152/ajpcell.00296.2013","title":"VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCε-dependent manner","year":2014,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Cystic Fibrosis Canada","keywords":"Cystic fibrosis transmembrane conductance regulator; Vasoactive intestinal peptide; Cell biology; Chemistry; Protein kinase C; Signal transduction; Biology; Receptor; Biochemistry; Neuropeptide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001058574,0.000197861,0.0003576414,0.0002148867,0.0002842723,0.0003568919,0.0001846757,0.0003429948,0.001333187],"category_scores_gemma":[0.0001001061,0.0001343863,0.0003563177,0.000198469,0.0002094277,0.0002107301,0.0001843986,0.0008456144,0.0003323304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006053149,"about_ca_system_score_gemma":0.00023891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003355578,"about_ca_topic_score_gemma":0.00349653,"domain_scores_codex":[0.9998291,0.00001638348,0.00001353555,0.00003802842,0.00004934924,0.00005358802],"domain_scores_gemma":[0.9999281,0.00001119073,0.00001582144,0.000009372474,0.00001384319,0.00002165401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001321751,0.00001698133,0.0002192821,0.0000350086,0.000003551478,0.00005692556,0.000021786,0.0000349218,0.9986473,0.00005955351,0.0001049961,0.0006675092],"study_design_scores_gemma":[0.00009103757,0.0004096646,0.04093826,0.00001763357,0.00004990018,0.0005336072,0.0001825165,0.003942519,0.9440213,0.000110382,0.009687518,0.00001574607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903315,0.004630389,0.001603425,0.0003560291,0.00006517498,0.00002219659,0.000854675,0.0001182946,0.002018353],"genre_scores_gemma":[0.9932197,0.001461395,0.001705789,0.0001882417,0.00001887846,0.00004709595,0.001010684,0.00001857231,0.00232981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003355578,"threshold_uncertainty_score":0.006672144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007713254129903808,"score_gpt":0.2176998746647587,"score_spread":0.2099866205348549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}