{"id":"W2332334694","doi":"10.3727/096368911x603639","title":"Evidence of Endoplasmic Reticulum Stress Mediating Cell Death in Transplanted Human Islets","year":2011,"lang":"en","type":"article","venue":"Cell Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Unfolded protein response; Islet; Endoplasmic reticulum; Transplantation; Programmed cell death; Apoptosis; Biology; Endocrinology; Internal medicine; Cell biology; Medicine; Diabetes mellitus; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001828378,0.0001434023,0.0002733272,0.0001800259,0.00003517582,0.000004158748,0.00006947239,0.0000975121,0.0002635032],"category_scores_gemma":[0.00001820953,0.0001339404,0.00006680306,0.000170163,0.00004282708,0.0001219521,0.000002325723,0.0001517594,0.00001703005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002108043,"about_ca_system_score_gemma":0.00004675988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002112698,"about_ca_topic_score_gemma":0.00002998431,"domain_scores_codex":[0.9988543,0.00007225968,0.000419624,0.0002237042,0.0002236482,0.0002065091],"domain_scores_gemma":[0.9994044,0.000181069,0.000120348,0.0001534128,0.00005492886,0.00008586107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003529096,0.0002344174,0.2580644,0.002631647,0.00001075743,0.00008138221,0.00619669,0.0000159279,0.7322872,0.00003422609,0.000004050707,0.00008643176],"study_design_scores_gemma":[0.002021805,0.0002747254,0.1409513,0.001486454,0.0001967036,0.00001256419,0.0002943896,0.000230454,0.854398,0.00002562528,0.000001315025,0.0001066681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772951,0.0002968543,0.0006027838,0.00001116499,0.00009358043,0.0002936759,0.00002964907,0.00004158653,0.02133558],"genre_scores_gemma":[0.9974172,0.0009723375,0.001228811,0.000047881,0.0000258012,0.00001974666,0.0001377321,0.00001641415,0.0001340777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1221108,"threshold_uncertainty_score":0.5461932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04861748918185971,"score_gpt":0.2633397031991889,"score_spread":0.2147222140173292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}