{"id":"W2332334694","doi":"10.3727/096368911x603639","title":"Evidence of Endoplasmic Reticulum Stress Mediating Cell Death in Transplanted Human Islets","year":2011,"lang":"en","type":"article","venue":"Cell Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Unfolded protein response; Islet; Endoplasmic reticulum; Transplantation; Programmed cell death; Apoptosis; Biology; Endocrinology; Internal medicine; Cell biology; Medicine; Diabetes mellitus; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002270103,0.0001895758,0.0002183432,0.0001816209,0.00008663387,0.000219514,0.0001117296,0.0002289895,0.001098635],"category_scores_gemma":[0.0001952442,0.00007988405,0.0001918291,0.0001640362,0.0001739029,0.0001685557,0.00017126,0.0004578858,0.0002325249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007332326,"about_ca_system_score_gemma":0.00008217055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006882205,"about_ca_topic_score_gemma":0.00005769879,"domain_scores_codex":[0.9998629,0.00002649767,0.0000166047,0.00002798151,0.00004354742,0.00002255232],"domain_scores_gemma":[0.9998251,0.00004727002,0.00003880235,0.00003721713,0.00001999379,0.00003161169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005790853,0.0000589921,0.002307621,0.00005876318,0.00001669138,0.0003639937,0.00004052407,0.00003210041,0.9946299,0.00004433444,0.00002899206,0.001838919],"study_design_scores_gemma":[0.00007794423,0.002026926,0.06383606,0.00002029393,0.00008510088,0.005137362,0.0001818391,0.0009444618,0.9254386,0.0001494108,0.002092509,0.000009420873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952982,0.002129484,0.001835098,0.00002427341,0.00002744359,0.00001346565,0.0001141044,0.00001973531,0.000538294],"genre_scores_gemma":[0.997065,0.001177553,0.0007408857,0.00003530271,0.00001371613,0.0000184386,0.0003686267,0.000008630995,0.0005718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001098635,"threshold_uncertainty_score":0.003675282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04861748918185971,"score_gpt":0.2633397031991889,"score_spread":0.2147222140173292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}