{"id":"W2332473811","doi":"10.1097/00024382-200306001-00073","title":"OXIDANTS IN HEMORRHAGIC SHOCK INDUCE LIPID RAFT RECRUITMENT OF TOLL LIKE RECEPTOR-4 (TLR-4).","year":2003,"lang":"en","type":"article","venue":"Shock","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Toll-like receptor; Hemorrhagic shock; Lipid raft; Toll; Raft; Shock (circulatory); Chemistry; Immunology; Receptor; Medicine; Cell biology; Biology; Innate immune system; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000326614,0.0002367861,0.0002862512,0.00007890004,0.00003299449,0.00001248843,0.0002283757,0.0002676675,0.0001341899],"category_scores_gemma":[0.000111161,0.0002344825,0.0001273769,0.0001906868,0.00005046409,0.000005112529,0.00008074344,0.000158506,0.00004724593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005244576,"about_ca_system_score_gemma":0.0001816762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003173044,"about_ca_topic_score_gemma":0.0001128093,"domain_scores_codex":[0.9983569,0.000154271,0.0004154837,0.0004692918,0.0001928105,0.0004112345],"domain_scores_gemma":[0.9991255,0.00001456189,0.0001074301,0.0005490845,0.00006186755,0.0001415782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007685475,0.0001615315,0.003276487,0.00003316414,0.00002948573,0.00000965259,0.00008426222,0.00002475536,0.9872705,0.0001174064,0.004331987,0.004583868],"study_design_scores_gemma":[0.0008519217,0.0002615146,0.0006855016,0.00003058587,0.00001074142,0.00001439411,0.0001547487,0.00001650861,0.820318,0.00006081647,0.1773178,0.0002774515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869797,0.000996163,0.000126379,0.00008688383,0.000420548,0.0004023962,0.00001658847,0.00001327037,0.01095807],"genre_scores_gemma":[0.9939864,0.0003046826,0.001852,0.0004288825,0.0001389447,0.00004990484,0.0000573921,0.00003745861,0.003144382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1729859,"threshold_uncertainty_score":0.9561918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02441696994556124,"score_gpt":0.2675191721031596,"score_spread":0.2431022021575983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}