{"id":"W2332498943","doi":"10.1093/toxsci/kfr135","title":"Modeling of the Internal Kinetics of Benzo(a)pyrene and 3-Hydroxybenzo(a)pyrene Biomarker from Rat Data","year":2011,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Pyrene; Benzo(a)pyrene; Chemistry; Toxicokinetics; Adipose tissue; Kinetics; Urine; Excretion; Metabolism; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006469793,0.0001495177,0.0002327528,0.0000255905,0.00009908473,0.00002044717,0.001898681,0.00009886095,0.003602078],"category_scores_gemma":[0.0004381,0.0000815652,0.00003775762,0.000447418,0.001974317,0.0002732261,0.001992602,0.0001113149,0.00001257908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003640449,"about_ca_system_score_gemma":0.00002011435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008635036,"about_ca_topic_score_gemma":0.0003451686,"domain_scores_codex":[0.998172,0.0001111795,0.0004179372,0.0004732411,0.0005109581,0.0003147034],"domain_scores_gemma":[0.9990159,0.0001194401,0.0001931732,0.0005425853,0.000003316628,0.000125616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000415176,0.0002892421,0.03821045,0.000002244813,0.00001822057,0.000002978203,0.0004601116,0.0002987413,0.9228553,0.00009387586,0.0001137503,0.03761362],"study_design_scores_gemma":[0.0003864574,0.0006119837,0.6367822,0.00004024931,0.00004838148,0.00001372024,0.0002518314,0.1255303,0.2294306,0.006547309,0.00008784684,0.0002690576],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924265,0.0001179405,0.0007916999,0.0001962721,0.0001913614,0.0001267818,0.0001364045,0.00001594673,0.005997135],"genre_scores_gemma":[0.9959103,0.00003186748,0.003857036,0.0001382185,0.00001718819,8.072516e-7,6.555795e-7,0.0000050399,0.00003892766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6934246,"threshold_uncertainty_score":0.9973088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1236921038816746,"score_gpt":0.2856664462431668,"score_spread":0.1619743423614922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}