{"id":"W2332568822","doi":"10.1056/jp200007180000003","title":"St. John's Wort is a CYP3A4 Inducer","year":2000,"lang":"en","type":"article","venue":"Journal watch","topic":"Psychology, Coaching, and Therapy","field":"Psychology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Inducer; CYP3A4; Traditional medicine; Pharmacology; Internal medicine; Biology; Genetics; Cytochrome P450","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006128201,0.0002155116,0.0002837317,0.0001055872,0.0002718171,0.0000804662,0.0004222868,0.0002652479,0.1002933],"category_scores_gemma":[0.00000806316,0.0001743716,0.0002092764,0.000227428,0.00006711068,0.0001436042,0.00001421809,0.00112652,0.003739657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006849668,"about_ca_system_score_gemma":0.00003644353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007117535,"about_ca_topic_score_gemma":0.00001311705,"domain_scores_codex":[0.9982641,0.0001738507,0.0004093834,0.0003209004,0.0002598143,0.0005719121],"domain_scores_gemma":[0.9990525,0.00004995622,0.0001420075,0.0004503606,0.00005368233,0.0002514939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003715637,0.0004658235,0.008220703,0.000002001673,0.0003282698,0.0004266381,0.009847006,0.000002124225,0.0002881429,0.0005308522,0.8255656,0.1539512],"study_design_scores_gemma":[0.001647246,0.0002244105,0.02904265,0.00001781429,0.00002602472,0.001899138,0.0002767164,0.000002869874,0.00004252629,0.01130666,0.95527,0.0002439438],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7955251,0.0006401416,0.0001081961,0.01748385,0.002391958,0.00009714635,0.000009698429,0.0000539833,0.1836899],"genre_scores_gemma":[0.8546734,0.00135378,0.000207151,0.01191575,0.002251444,0.0000124459,0.000003745242,0.00005872847,0.1295235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1537073,"threshold_uncertainty_score":0.997036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02833102661434063,"score_gpt":0.3514761880272346,"score_spread":0.323145161412894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}