{"id":"W2332732552","doi":"10.1016/j.mehy.2016.04.012","title":"A stable epoxide as a potential endogenous estrogen metabolite: Possible significance in breast cancer?","year":2016,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Estrone; Metabolite; Estrogen; Chemistry; Carcinogen; Metabolism; Epoxide; Biochemistry; Hydroxylation; Enzyme; Biology; Endocrinology; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005000252,0.000296641,0.0001925281,0.0004142899,0.0002465272,0.0004503025,0.0005583045,0.001191312,0.006476858],"category_scores_gemma":[0.0005632119,0.0001265254,0.0002527705,0.0002414157,0.0007624159,0.000859733,0.000276595,0.0004427757,0.0007588866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002082859,"about_ca_system_score_gemma":0.0002644175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001955965,"about_ca_topic_score_gemma":0.0001471162,"domain_scores_codex":[0.9999366,0.0000191696,0.000004339091,0.00001711985,0.000009457907,0.0000134553],"domain_scores_gemma":[0.9997279,0.0001124652,0.00005242019,0.00003372757,0.00003421685,0.00003926098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.009078608,0.001145845,0.05511565,0.00149127,0.0003001472,0.03107491,0.0007351415,0.002087603,0.6238492,0.08438794,0.004598163,0.1861355],"study_design_scores_gemma":[0.0006477611,0.009469873,0.04360263,0.0001972452,0.0005068799,0.02802932,0.001684729,0.003772925,0.6905738,0.07882982,0.142588,0.00009706985],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.858255,0.07816192,0.02147821,0.01571366,0.001100955,0.0001397495,0.0006443391,0.0001667868,0.02433945],"genre_scores_gemma":[0.9694286,0.01530582,0.00234817,0.0009640851,0.0008881857,0.0000293731,0.0002545981,0.00001188246,0.01076932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006476858,"threshold_uncertainty_score":0.02166724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01020299949374483,"score_gpt":0.2427299523968487,"score_spread":0.2325269529031039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}