{"id":"W2332777704","doi":"10.1038/nature17399","title":"Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1","year":2016,"lang":"en","type":"article","venue":"Nature","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":453,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; JPB Foundation","keywords":"Thermogenesis; Thermogenin; Brown adipose tissue; Mitochondrion; Oxidative phosphorylation; Adipose tissue; Uncoupling protein; Respiration; Reactive oxygen species; Chemistry; Cell biology; Biology; Biochemistry; Endocrinology; Internal medicine; Medicine; Anatomy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001986769,0.0002248544,0.0002359825,0.0001644711,0.0003011732,0.0004368792,0.0001599386,0.0002228065,0.002638209],"category_scores_gemma":[0.0002740669,0.0001993535,0.0003096632,0.0001565351,0.0002969619,0.0004333542,0.0005576735,0.0005121402,0.0002552095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003460474,"about_ca_system_score_gemma":0.0001862654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006725669,"about_ca_topic_score_gemma":0.001266646,"domain_scores_codex":[0.9998649,0.00002081882,0.000009355148,0.00004181796,0.00002231493,0.00004088179],"domain_scores_gemma":[0.999843,0.00002137206,0.00005382407,0.00002330334,0.00002344773,0.0000349117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002305218,0.0000558079,0.002582813,0.00007950351,0.00003375392,0.00008044275,0.0001010025,0.0001828819,0.9876707,0.0006429905,0.0003821671,0.005882708],"study_design_scores_gemma":[0.0001147443,0.0003601222,0.08677486,0.00002777706,0.0000606189,0.0002710581,0.0003927674,0.002755248,0.9035949,0.0009398519,0.004688866,0.00001924664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939921,0.001981223,0.001888845,0.0004932375,0.00008194574,0.00001101571,0.00032177,0.00005354407,0.001176152],"genre_scores_gemma":[0.9966336,0.0005509912,0.0007086082,0.00006515208,0.00002195835,0.00001006692,0.0003049186,0.00002569261,0.001679035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002638209,"threshold_uncertainty_score":0.008825719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006752482417397992,"score_gpt":0.2498694493801001,"score_spread":0.2431169669627021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}