{"id":"W2332781348","doi":"10.1074/jbc.m115.701482","title":"Benzothiazole Amphiphiles Promote the Formation of Dendritic Spines in Primary Hippocampal Neurons","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; University of California, San Diego; National Institutes of Health; Manitoba Medical Service Foundation","keywords":"Dendritic spine; SPINE (molecular biology); Hippocampal formation; Hippocampus; Neuroscience; Excitatory postsynaptic potential; Benzothiazole; Cognitive decline; Chemistry; Biology; Medicine; Dementia; Disease; Cell biology; Internal medicine; Inhibitory postsynaptic potential; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008751443,0.0002044196,0.0001529201,0.0001236537,0.0001376657,0.0001284791,0.0001170566,0.000168641,0.0007175865],"category_scores_gemma":[0.0001031581,0.00009313066,0.0001274761,0.00009143077,0.0001040541,0.00009917032,0.0001196466,0.0003213927,0.0002080213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001803825,"about_ca_system_score_gemma":0.0001844547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00145421,"about_ca_topic_score_gemma":0.00430222,"domain_scores_codex":[0.9999335,0.000008193469,0.000003983543,0.000008097764,0.00002739543,0.00001890568],"domain_scores_gemma":[0.9999386,0.00001265128,0.00001409829,0.000004795983,0.00001202104,0.00001784232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000292648,0.00001085048,0.0000376631,0.00001553861,0.000001223308,0.000008502689,0.00000494883,0.0000171664,0.9993754,0.00001172506,0.00001570002,0.0004720811],"study_design_scores_gemma":[0.00001349331,0.0004275829,0.004722676,0.000004266206,0.000007316016,0.00004212381,0.000008862338,0.0002527761,0.9936427,0.000008475678,0.0008671843,0.000002499387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953167,0.001194443,0.001356585,0.00005972961,0.00001298652,0.00004607907,0.000200108,0.00005008184,0.001763235],"genre_scores_gemma":[0.9946575,0.001498836,0.001664566,0.00004120191,0.000009501106,0.00005528203,0.000253226,0.00001104343,0.001808782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00145421,"threshold_uncertainty_score":0.002891541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03466137093687676,"score_gpt":0.2937721146251734,"score_spread":0.2591107436882967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}