{"id":"W2332871558","doi":"10.18632/oncotarget.8396","title":"Neuraminidase-1: A novel therapeutic target in multistage tumorigenesis","year":2016,"lang":"en","type":"review","venue":"Oncotarget","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Kingston Health Sciences Centre","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Receptor tyrosine kinase; Cancer research; Carcinogenesis; Angiogenesis; Metastasis; Growth factor receptor; Growth factor receptor inhibitor; Tyrosine kinase; Cancer; Epidermal growth factor; Medicine; Vascular endothelial growth factor; Growth factor; Epidermal growth factor receptor; Fibroblast growth factor; Fibroblast growth factor receptor; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002280328,0.0004671457,0.0003197976,0.0003227954,0.0001563912,0.0006387947,0.0003615861,0.0005970025,0.001017985],"category_scores_gemma":[0.00008640443,0.0001191954,0.0002369748,0.0001504923,0.0002551015,0.0005402307,0.0003727633,0.0009567323,0.0005422609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000479768,"about_ca_system_score_gemma":0.0002924937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000242062,"about_ca_topic_score_gemma":0.0005343482,"domain_scores_codex":[0.9999419,0.000008212751,0.000003198498,0.000007977002,0.00001654555,0.00002209027],"domain_scores_gemma":[0.9999661,0.000003839155,0.000009646085,0.000002548736,0.000006599869,0.00001120235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000980158,0.0003914116,0.001099232,0.0006088241,0.00003353751,0.001031595,0.0000817679,0.0006649683,0.83799,0.004753768,0.003127512,0.1492372],"study_design_scores_gemma":[0.000601473,0.004646133,0.00687313,0.0002667178,0.0001551142,0.01104405,0.0001802539,0.005144071,0.8136919,0.003035637,0.154306,0.00005560247],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6882591,0.2556981,0.0231464,0.008104357,0.001100094,0.0004274267,0.0004392773,0.0005580738,0.02226723],"genre_scores_gemma":[0.8861352,0.09158999,0.01001233,0.00107816,0.0002762178,0.0001161427,0.0003182057,0.00003572029,0.01043796],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001017985,"threshold_uncertainty_score":0.00348103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0460573209631586,"score_gpt":0.3749101970799412,"score_spread":0.3288528761167826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}