{"id":"W2332871558","doi":"10.18632/oncotarget.8396","title":"Neuraminidase-1: A novel therapeutic target in multistage tumorigenesis","year":2016,"lang":"en","type":"review","venue":"Oncotarget","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Kingston Health Sciences Centre","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Receptor tyrosine kinase; Cancer research; Carcinogenesis; Angiogenesis; Metastasis; Growth factor receptor; Growth factor receptor inhibitor; Tyrosine kinase; Cancer; Epidermal growth factor; Medicine; Vascular endothelial growth factor; Growth factor; Epidermal growth factor receptor; Fibroblast growth factor; Fibroblast growth factor receptor; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001799269,0.0004863859,0.0009043773,0.0001582496,0.00005306938,0.00003576894,0.0004203726,0.0003361998,0.0002266288],"category_scores_gemma":[0.0000510194,0.0003440214,0.0004307476,0.0001881777,0.00007900404,0.000003958128,0.0001684981,0.0001977968,0.0002594646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000162877,"about_ca_system_score_gemma":0.0005678111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001286401,"about_ca_topic_score_gemma":0.0001677048,"domain_scores_codex":[0.9978325,0.000136833,0.0004329574,0.0007529516,0.0002341338,0.0006106271],"domain_scores_gemma":[0.9989139,0.000042606,0.0001727022,0.0006537591,0.00003952193,0.0001775109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001134772,0.0007677046,0.0009521963,0.003401403,0.0007022418,0.000233582,0.00001704437,9.057649e-7,0.002167423,0.00005377896,0.003070328,0.9885199],"study_design_scores_gemma":[0.0008230415,0.0002034833,0.00007728577,0.001158563,0.00005824652,0.00002653487,0.000002106404,0.000001284664,0.0001924511,0.00001751122,0.9970613,0.0003781867],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001422892,0.997087,0.0001746953,0.00002507673,0.0001911004,0.0007448855,0.0008581017,0.00001477182,0.0007620626],"genre_scores_gemma":[0.0002977549,0.9937609,0.0003174133,0.0000680177,0.0003550297,0.0004181141,0.0009774922,0.0001053314,0.003699919],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.993991,"threshold_uncertainty_score":0.9999012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0460573209631586,"score_gpt":0.3749101970799412,"score_spread":0.3288528761167826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}