{"id":"W2332900097","doi":"10.1021/ol202840s","title":"Modular Synthesis of Functionalized Bis-bispidine Tetraazamacrocycles","year":2011,"lang":"en","type":"article","venue":"Organic Letters","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Modular design; Chemistry; Combinatorial chemistry; Computer science; Programming language","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001850232,0.0001513254,0.0003810375,0.0001093023,0.00004966823,0.0000061126,0.0001189608,0.00005112751,0.007538397],"category_scores_gemma":[0.0002090965,0.0001114596,0.0001477104,0.0001586768,0.0001094481,0.00006607878,0.00003549284,0.00009045521,0.0001082591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003018425,"about_ca_system_score_gemma":0.00003394418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006271687,"about_ca_topic_score_gemma":0.000002966825,"domain_scores_codex":[0.9989858,0.00005580769,0.0003020796,0.0002133252,0.0002502239,0.0001928193],"domain_scores_gemma":[0.9993495,0.00007622059,0.00009601278,0.000344621,0.00005278966,0.00008087838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00017832,0.00009641361,0.002856,0.00009906448,0.0001597459,0.000009872283,0.0001341776,2.599068e-7,0.993341,0.0001883767,0.0008789311,0.002057804],"study_design_scores_gemma":[0.000400903,0.00008882121,0.04069853,0.00009029225,0.0002057463,0.00004667603,0.00006266186,0.00001766081,0.953547,0.00005024194,0.004648324,0.0001431601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936696,0.0003863242,0.0004560002,0.001514189,0.0001376599,0.0001505234,0.000005931026,0.00006103815,0.003618775],"genre_scores_gemma":[0.995681,0.00004236701,0.002494626,0.001356374,0.00009025794,0.00001334819,0.000003441308,0.00003563874,0.0002828847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03979405,"threshold_uncertainty_score":0.9933689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04762508979835409,"score_gpt":0.2243180324134539,"score_spread":0.1766929426150998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}