{"id":"W2332924145","doi":"10.1021/acs.jproteome.5b00016","title":"Deregulated Tyrosine–Phenylalanine Metabolism in Pulmonary Tuberculosis Patients","year":2015,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Grand Challenges Canada; Department of Biotechnology, Ministry of Science and Technology, India; Bill and Melinda Gates Foundation","keywords":"Metabolome; Medicine; Phenylalanine; Tyrosine; Urine; Internal medicine; Asymptomatic; Gastroenterology; Metabolite; Chemistry; Biochemistry; Amino acid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002371634,0.000130817,0.0003093835,0.0004571874,0.00005663873,0.00003369719,0.0003045139,0.0001232883,0.00002119987],"category_scores_gemma":[0.001003989,0.0001017017,0.00009701807,0.0005671699,0.0000939699,0.00001313061,0.0002467059,0.0003923124,0.00000870099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006230841,"about_ca_system_score_gemma":0.0001904368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004045441,"about_ca_topic_score_gemma":0.00001192648,"domain_scores_codex":[0.9979177,0.000306049,0.0004524647,0.0002068324,0.0007078982,0.0004090885],"domain_scores_gemma":[0.9981677,0.00002015125,0.0001517984,0.0002262869,0.00122629,0.0002077582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001021465,0.0008054185,0.05427458,0.00004608117,0.0002537362,0.0000691756,0.000148756,0.00004703702,0.9330854,0.0001746587,0.007268926,0.002804721],"study_design_scores_gemma":[0.007635183,0.003298345,0.5025309,0.0001425093,0.00006734781,0.0001855658,0.0007190136,0.0001789727,0.3919756,0.004237351,0.08837235,0.000656903],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921342,0.005565324,0.00005990424,0.0006110311,0.0001609299,0.0002992462,0.000006979139,0.000002158053,0.001160236],"genre_scores_gemma":[0.996675,0.0009428651,0.001572158,0.00002608115,0.0003062918,0.00001604627,0.00001181071,0.0000211503,0.0004285866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5411099,"threshold_uncertainty_score":0.4147274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04888639934848348,"score_gpt":0.3366716800432957,"score_spread":0.2877852806948122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}