{"id":"W2332987089","doi":"10.2174/1871523012666131229132519","title":"A Novel Method Aimed at Counteracting the Side Effects Caused by Prostaglandin E&lt;sub&gt;2&lt;/sub&gt; Deficiency During Non-Steroidal Anti-Inflammatory Drug Therapy","year":2014,"lang":"en","type":"article","venue":"Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto East General Hospital","funders":"","keywords":"Pharmacology; Prostaglandin E2; Drug; In vivo; Chemistry; Endogeny; Diclofenac; Cyclooxygenase; Medicine; Internal medicine; Enzyme; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001316195,0.0003007861,0.0004065626,0.0003490598,0.0001660217,0.0002574366,0.0003423917,0.0003923067,0.001525393],"category_scores_gemma":[0.0001376348,0.0001358098,0.0003321274,0.0001602852,0.0002142257,0.0003222558,0.000215493,0.000572258,0.0003205726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001098663,"about_ca_system_score_gemma":0.0002410985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003126441,"about_ca_topic_score_gemma":0.0006434081,"domain_scores_codex":[0.9998882,0.00001528338,0.000007724306,0.00003064564,0.00004439494,0.00001377662],"domain_scores_gemma":[0.9999475,0.00001081522,0.00001533313,0.000006174669,0.00000959452,0.00001058482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000357792,0.0001798347,0.0001901577,0.0003545818,0.00002350662,0.0001844877,0.00002303089,0.00007956679,0.9626703,0.0002004466,0.0003059456,0.03543026],"study_design_scores_gemma":[0.0001990213,0.003027993,0.004367216,0.00004415604,0.0001644545,0.002084825,0.00005291817,0.001814032,0.9657123,0.0001469251,0.02235475,0.00003122699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8504089,0.05194085,0.08638195,0.0008319197,0.0008799975,0.0006494267,0.0005211061,0.0008976262,0.00748827],"genre_scores_gemma":[0.9071047,0.01261445,0.07031474,0.0005604355,0.0001643011,0.0003429347,0.0003943294,0.0000592053,0.008444983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001525393,"threshold_uncertainty_score":0.005102992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007867843312715285,"score_gpt":0.2521577908786573,"score_spread":0.244289947565942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}