{"id":"W2332990668","doi":"10.1021/ja5081184","title":"Molecular Recognition of <i>Brucella</i> A and M Antigens Dissected by Synthetic Oligosaccharide Glycoconjugates Leads to a Disaccharide Diagnostic for Brucellosis","year":2014,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Brucella: diagnosis, epidemiology, treatment","field":"Veterinary","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Glycoconjugate; Antigen; Chemistry; Brucella; Disaccharide; Monoclonal antibody; Epitope; Polyclonal antibodies; Antibody; Brucellosis; Microbiology; Polysaccharide; Oligosaccharide; Biochemistry; Virology; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118048,0.0002765336,0.0001118146,0.0001196958,0.00007340078,0.000205408,0.0001234635,0.0002061648,0.0004090446],"category_scores_gemma":[0.0001102556,0.0001445273,0.000164085,0.00009961046,0.0001917912,0.0001063779,0.0001452109,0.0003501227,0.0002209868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002607166,"about_ca_system_score_gemma":0.0001659764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002928612,"about_ca_topic_score_gemma":0.0002904819,"domain_scores_codex":[0.9999307,0.00001441045,0.000004701906,0.00001309244,0.00001785983,0.00001924545],"domain_scores_gemma":[0.9999403,0.000007757753,0.00001881092,0.000006145885,0.00000710846,0.00001983027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004753896,0.00001500486,0.00008108435,0.00001275441,0.000001563982,0.00002021911,0.000004215751,0.00009717177,0.998633,0.0001552713,0.00001438181,0.0009179438],"study_design_scores_gemma":[0.00001029045,0.0003389994,0.0008722285,0.000003708956,0.000005800542,0.00008108059,0.000005093681,0.0004518436,0.9969138,0.00004129529,0.001273765,0.000002053418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904179,0.0007251471,0.005214764,0.0001109076,0.00003787941,0.00004117049,0.00009321787,0.00007568145,0.003283343],"genre_scores_gemma":[0.9904814,0.0008435815,0.006427531,0.0001142316,0.00001214088,0.00002514716,0.0001774179,0.00001745534,0.00190096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004090446,"threshold_uncertainty_score":0.001891613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02141263436931015,"score_gpt":0.2932566968926578,"score_spread":0.2718440625233477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}