{"id":"W2332990668","doi":"10.1021/ja5081184","title":"Molecular Recognition of <i>Brucella</i> A and M Antigens Dissected by Synthetic Oligosaccharide Glycoconjugates Leads to a Disaccharide Diagnostic for Brucellosis","year":2014,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Brucella: diagnosis, epidemiology, treatment","field":"Veterinary","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Glycoconjugate; Antigen; Chemistry; Brucella; Disaccharide; Monoclonal antibody; Epitope; Polyclonal antibodies; Antibody; Brucellosis; Microbiology; Polysaccharide; Oligosaccharide; Biochemistry; Virology; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006355375,0.0003219396,0.000937794,0.00003568598,0.0001022029,0.00002590768,0.0004516404,0.0001208186,0.00001586851],"category_scores_gemma":[0.005091066,0.0002326154,0.0006576723,0.0004002171,0.0005361578,0.00006414609,0.0001781884,0.0003146244,0.000005283569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001527343,"about_ca_system_score_gemma":0.00004536054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001889626,"about_ca_topic_score_gemma":0.000002226342,"domain_scores_codex":[0.9977539,0.0002678783,0.0008715296,0.0003801696,0.0002767762,0.0004498092],"domain_scores_gemma":[0.9937803,0.004094152,0.001180207,0.0003745168,0.0003010534,0.000269798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003284141,0.0003015212,0.01303566,0.0000794641,0.0002902987,0.000003666826,0.0002922009,0.00001376398,0.968838,0.0000105021,0.01391161,0.002894901],"study_design_scores_gemma":[0.001024562,0.001546658,0.004698741,0.0003464143,0.0006112604,0.0001836689,0.0002325129,0.0003406839,0.9888334,0.0009760248,0.0008367373,0.000369309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932736,0.0004823237,0.001631826,0.003782818,0.0001537172,0.0004956367,0.0001412335,0.00002203231,0.00001687585],"genre_scores_gemma":[0.9897873,0.0005464663,0.007362918,0.002040398,0.0001196633,0.00007560766,0.00001045921,0.00005160849,0.000005543679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01999543,"threshold_uncertainty_score":0.9485779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02141263436931015,"score_gpt":0.2932566968926578,"score_spread":0.2718440625233477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}