{"id":"W2333032265","doi":"10.1021/bi400836g","title":"Functional Characterization of <i>Staphylococcus epidermidis</i> IcaB, a De-<i>N</i>-acetylase Important for Biofilm Formation","year":2013,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biofilm; Enzyme; Chemistry; Acetylation; Biochemistry; Staphylococcus epidermidis; Polysaccharide; Residue (chemistry); Enzyme kinetics; Bacteria; Stereochemistry; Active site; Biology; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001613823,0.0004637812,0.0003136744,0.000125482,0.0001196685,0.0003619569,0.0002061626,0.0003155846,0.0005662318],"category_scores_gemma":[0.0002331776,0.00009989544,0.0002876862,0.0002157827,0.0001851521,0.0001568357,0.0001219498,0.0004190702,0.0004558696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003717101,"about_ca_system_score_gemma":0.0002491387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003222829,"about_ca_topic_score_gemma":0.00193357,"domain_scores_codex":[0.9998696,0.00001407322,0.000008704559,0.00003044397,0.00005608866,0.00002099321],"domain_scores_gemma":[0.999864,0.00002173978,0.00002514342,0.00001398623,0.00004181956,0.00003327177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000145943,0.00001122272,0.0001273112,0.0000128587,0.000002803171,0.00001117662,0.000006361029,0.00002169549,0.9993377,0.00001460666,0.00001750823,0.0004219765],"study_design_scores_gemma":[0.00000380803,0.0001066846,0.007021606,0.000004305568,0.0000110757,0.0002169612,0.00002394656,0.0006514585,0.9896747,0.0000149642,0.002265172,0.000005229121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922374,0.001565563,0.003641197,0.0001323707,0.00002536831,0.00002559387,0.000918365,0.00004543902,0.001408712],"genre_scores_gemma":[0.9852912,0.001114434,0.006066241,0.0001094136,0.00001161845,0.0000283956,0.003865105,0.00005464534,0.00345887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003222829,"threshold_uncertainty_score":0.006408155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008950097851749316,"score_gpt":0.2115758601044633,"score_spread":0.202625762252714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}