{"id":"W2333032265","doi":"10.1021/bi400836g","title":"Functional Characterization of <i>Staphylococcus epidermidis</i> IcaB, a De-<i>N</i>-acetylase Important for Biofilm Formation","year":2013,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biofilm; Enzyme; Chemistry; Acetylation; Biochemistry; Staphylococcus epidermidis; Polysaccharide; Residue (chemistry); Enzyme kinetics; Bacteria; Stereochemistry; Active site; Biology; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001321709,0.0001656958,0.0001565321,0.00002424362,0.00007165388,0.00003008926,0.00008938766,0.0002242759,0.00005588766],"category_scores_gemma":[0.0000811031,0.0001633471,0.0001370009,0.00006659803,0.00006515036,0.00001427353,0.00004454092,0.0000465079,0.000005177967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002081688,"about_ca_system_score_gemma":0.0000981023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001463164,"about_ca_topic_score_gemma":0.000001118608,"domain_scores_codex":[0.9989855,0.00001669711,0.0003851224,0.000263712,0.00008801875,0.0002609673],"domain_scores_gemma":[0.999181,0.00001031412,0.0002632005,0.0002612525,0.0001865055,0.00009775426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008645617,0.00005327733,0.0004218341,0.0001088486,0.00002387104,2.518154e-7,0.000009968822,9.937108e-7,0.9949978,0.00001371276,0.00323851,0.001044463],"study_design_scores_gemma":[0.0004827587,0.00008541664,0.002321709,0.0000220596,0.00001712426,0.00001699941,0.00003203588,0.0001906322,0.9922513,0.00001789659,0.004372395,0.0001896439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964324,0.0001058407,0.002415393,0.0002657047,0.0001303858,0.0003279306,0.0001916046,0.00001732601,0.0001134752],"genre_scores_gemma":[0.9950927,0.00006779427,0.001390894,0.0003024107,0.000446477,0.00007981655,0.002304615,0.00002327358,0.000291998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002746484,"threshold_uncertainty_score":0.6661102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008950097851749316,"score_gpt":0.2115758601044633,"score_spread":0.202625762252714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}