{"id":"W2333368946","doi":"10.1097/ftd.0000000000000021","title":"Similar MPA Exposure on Modified Release and Regular Tacrolimus","year":2013,"lang":"en","type":"article","venue":"Therapeutic Drug Monitoring","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Tacrolimus; Mycophenolic acid; Pharmacokinetics; Medicine; Concomitant; Crossover study; Urology; Mycophenolate; Immunosuppression; Area under the curve; Randomization; Pharmacology; Transplantation; Internal medicine; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006057114,0.0001744653,0.0002199508,0.00006778645,0.0000948312,0.00003780777,0.00004871846,0.0000527931,0.0000378763],"category_scores_gemma":[0.000004539193,0.0001302189,0.00006233004,0.0000745409,0.00003075746,0.0000889931,0.000008450963,0.0001343057,0.00006119922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004061903,"about_ca_system_score_gemma":0.00001486759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007097064,"about_ca_topic_score_gemma":2.879236e-7,"domain_scores_codex":[0.9991208,0.00003424162,0.0001722041,0.0002178404,0.000230092,0.0002248408],"domain_scores_gemma":[0.9994314,0.00007474978,0.00004297004,0.0002508022,0.00004265566,0.0001573731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009831346,0.000835527,0.7071134,0.0007216388,0.001474108,0.0005016043,0.004920448,0.0005338976,0.03741436,0.001171576,0.00007916451,0.2442511],"study_design_scores_gemma":[0.006627121,0.0004965891,0.9411823,0.0008166123,0.0003608517,0.00007568341,0.000581371,0.0004937411,0.04724918,0.001314748,0.0004559077,0.0003458695],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958099,0.0008542676,0.00005104737,0.0009087104,0.0003212069,0.0003863386,0.000003324367,0.00008322852,0.001581987],"genre_scores_gemma":[0.9966906,0.0004566838,0.0003266411,0.0003197342,0.0002161929,0.00004539417,0.000006967547,0.0000299761,0.001907799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2439053,"threshold_uncertainty_score":0.5310172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02832990644399885,"score_gpt":0.2849476658293316,"score_spread":0.2566177593853328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}