{"id":"W2333427259","doi":"10.1021/es503712c","title":"Abnormal Ovarian DNA Methylation Programming during Gonad Maturation in Wild Contaminated Fish","year":2014,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Conseil Régional Aquitaine; Agence Nationale de la Recherche","keywords":"Gonad; Biology; DNA methylation; Epigenetics; Aromatase; Estrogen receptor; Methylation; Andrology; Gene; Internal medicine; Genetics; Endocrinology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006583526,0.0001019991,0.0001414468,0.0002058068,0.0001294215,0.0001468449,0.00009497347,0.0001559126,0.0008697419],"category_scores_gemma":[0.0001428007,0.0001339234,0.0001405895,0.0001085659,0.0001857877,0.0001234506,0.0001944257,0.0001769574,0.0001127746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001899641,"about_ca_system_score_gemma":0.0001597312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002464444,"about_ca_topic_score_gemma":0.005943624,"domain_scores_codex":[0.999943,0.00000506633,0.000004146806,0.00002533938,0.00001291373,0.000009542226],"domain_scores_gemma":[0.9999115,0.000009422326,0.00003921341,0.000006948144,0.00001942901,0.00001348826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002021393,0.000009242277,0.02323278,0.00002702426,0.00001355513,0.00005877615,0.000105151,0.00002672412,0.9746076,0.00003042795,0.00002268665,0.001663685],"study_design_scores_gemma":[0.00001078123,0.0004542208,0.8514299,0.00000773308,0.00004458389,0.0003045618,0.0003081591,0.0002231856,0.1456838,0.0001244777,0.001396581,0.00001203039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984691,0.0003522617,0.0004587734,0.00002567753,0.000005605143,0.000004792175,0.0002433009,0.000007148203,0.0004334232],"genre_scores_gemma":[0.9974137,0.0002565781,0.0005137835,0.00004230292,0.000003557654,0.00001490973,0.0002920188,0.000006702511,0.001456487],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002464444,"threshold_uncertainty_score":0.004900277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003287588818452535,"score_gpt":0.2068462312426499,"score_spread":0.2035586424241973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}