{"id":"W2333488286","doi":"10.1124/mol.114.093476","title":"Role of SAP97 in the Regulation of 5-HT2AR Endocytosis and Signaling","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"PDZ domain; HEK 293 cells; Gene knockdown; Cell biology; Internalization; Biology; Ankyrin repeat; Receptor; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002321114,0.0002590569,0.0003660785,0.0002387098,0.0003320922,0.0008732632,0.0003879599,0.0004192624,0.00169042],"category_scores_gemma":[0.0002117593,0.0001394322,0.0004195881,0.0001948847,0.0005309086,0.0006611326,0.000363623,0.0009050799,0.0005663778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004929058,"about_ca_system_score_gemma":0.0003198952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004853501,"about_ca_topic_score_gemma":0.0004160627,"domain_scores_codex":[0.9998562,0.00002037446,0.00001506516,0.00002261355,0.00004102556,0.00004471018],"domain_scores_gemma":[0.9998505,0.00003514993,0.00002833987,0.00002697273,0.00001968319,0.00003936647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001092707,0.00007414969,0.001865486,0.0001544191,0.00005338974,0.001668138,0.00006233047,0.0007006246,0.9731321,0.004853318,0.0004240067,0.01591945],"study_design_scores_gemma":[0.00008296598,0.0003689384,0.05856008,0.00004060635,0.00006204296,0.004727996,0.0003443393,0.007678168,0.9161298,0.004476734,0.007478826,0.00004948926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773839,0.008506007,0.006744368,0.0006173183,0.0000647972,0.00001435793,0.0004903024,0.0001427942,0.006036176],"genre_scores_gemma":[0.992699,0.002210974,0.001710646,0.00006758432,0.00002553837,0.00001237954,0.000390988,0.00002140171,0.00286156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00169042,"threshold_uncertainty_score":0.005654991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005161136667635055,"score_gpt":0.2408256091475777,"score_spread":0.2356644724799427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}