{"id":"W2333488286","doi":"10.1124/mol.114.093476","title":"Role of SAP97 in the Regulation of 5-HT2AR Endocytosis and Signaling","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"PDZ domain; HEK 293 cells; Gene knockdown; Cell biology; Internalization; Biology; Ankyrin repeat; Receptor; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004019809,0.0000831291,0.0001423898,0.00005082126,0.00002151659,0.00000347472,0.000130222,0.00008286663,0.00005612408],"category_scores_gemma":[0.00002690562,0.00006958354,0.00005059649,0.00007488651,0.00005985074,0.000002125532,0.0000479605,0.00005913646,4.329416e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003270062,"about_ca_system_score_gemma":0.00001431918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001727626,"about_ca_topic_score_gemma":0.00000244801,"domain_scores_codex":[0.9991723,0.0002379287,0.0002080527,0.0001674479,0.00008817424,0.0001261522],"domain_scores_gemma":[0.9996843,0.00002997996,0.0001035967,0.0001203654,0.00004007406,0.00002167961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004227035,0.00003278575,0.0003304705,0.00001596403,0.00002400926,4.949804e-7,0.0001169346,0.0006361689,0.9957641,0.0008634325,0.00002835607,0.002145035],"study_design_scores_gemma":[0.0005066028,0.0002050037,0.0005681338,0.000006089001,0.00002844251,0.000006173315,0.00008666067,0.000898958,0.9951268,0.0008360824,0.001664659,0.00006641189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949943,0.0007497527,0.003618006,0.00006651535,0.00004404458,0.0001398867,0.00000221809,0.000002093079,0.0003831282],"genre_scores_gemma":[0.9988731,0.00004911763,0.0007421637,0.0002422572,0.00004949721,0.00001411159,0.00001343041,0.00000957283,0.000006735087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003878759,"threshold_uncertainty_score":0.2837535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005161136667635055,"score_gpt":0.2408256091475777,"score_spread":0.2356644724799427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}