{"id":"W2333693876","doi":"10.1021/ac501341t","title":"Sequential Strand Displacement Beacon for Detection of DNA Coverage on Functionalized Gold Nanoparticles","year":2014,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"DNA; Molecular beacon; Multiple displacement amplification; Chemistry; Oligonucleotide; Colloidal gold; Fluorescence; DNA sequencing; A-DNA; Biophysics; Combinatorial chemistry; Nanotechnology; Molecular biology; Nanoparticle; Polymerase chain reaction; Biochemistry; DNA extraction; Biology; Gene; Materials science; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007626296,0.0006962748,0.0004511339,0.0008163194,0.0002224007,0.0002471638,0.0007515788,0.0009109721,0.001511865],"category_scores_gemma":[0.00103369,0.0004684756,0.0002706396,0.0005020081,0.0003850001,0.0004716624,0.0004824529,0.0008737469,0.0007205866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004856326,"about_ca_system_score_gemma":0.0003753361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004078014,"about_ca_topic_score_gemma":0.0007900666,"domain_scores_codex":[0.9993346,0.0001242983,0.00003114598,0.0001945757,0.0002738128,0.00004164789],"domain_scores_gemma":[0.9995183,0.0002582076,0.00007282239,0.00002932536,0.00007457029,0.00004686345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004139093,0.0000127855,0.0001145304,0.000144692,0.00000620066,0.00002452932,0.00003445572,0.0001687394,0.9901907,0.0005217562,0.0001851141,0.008554941],"study_design_scores_gemma":[0.00001529476,0.0001528112,0.0001970983,0.00001233824,0.000009090095,0.0001475096,0.000009775237,0.004240614,0.9908835,0.0001826226,0.004138354,0.00001102228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1984293,0.01048254,0.7827047,0.0004807746,0.0005238168,0.0003443861,0.000628629,0.002507201,0.003898645],"genre_scores_gemma":[0.4260701,0.004424694,0.561228,0.0003725748,0.00008716442,0.0005708219,0.0007485216,0.00009303902,0.006405089],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001511865,"threshold_uncertainty_score":0.005057693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059654535840942,"score_gpt":0.2710793528479709,"score_spread":0.2604828074895615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}