{"id":"W2334252516","doi":"10.1021/jo1017316","title":"Cleavage of an RNA Model Catalyzed by Dinuclear Zn(II) Complexes Containing Rate-Accelerating Pendants. Comparison of the Catalytic Benefits of H-Bonding and Hydrophobic Substituents","year":2010,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Metal-Organic Frameworks: Synthesis and Applications","field":"Chemistry","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Catalysis; Substituent; Medicinal chemistry; Enzyme kinetics; Reaction rate constant; Ligand (biochemistry); Stereochemistry; Kinetics; Polymer chemistry; Organic chemistry; Active site","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001862885,0.0004835162,0.0003059658,0.0001068985,0.00007302356,0.0002431376,0.000383567,0.0003303511,0.0005449846],"category_scores_gemma":[0.0003174994,0.0001698195,0.0001643534,0.0001393181,0.0001558619,0.0002201859,0.0002865507,0.0004228443,0.0002157735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002878552,"about_ca_system_score_gemma":0.0001252385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006834398,"about_ca_topic_score_gemma":0.001437698,"domain_scores_codex":[0.9998131,0.00002563812,0.00001477551,0.00006615352,0.00004243361,0.00003794044],"domain_scores_gemma":[0.9998833,0.00002470399,0.00003622829,0.00001122339,0.0000212395,0.00002328129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006979223,0.000008954055,0.00006097276,0.00003387663,0.000005619022,0.00001953611,0.00001532606,0.0001304122,0.9988359,0.00003062986,0.00001180272,0.0007772666],"study_design_scores_gemma":[0.000003246095,0.00008440517,0.0002030041,0.000001829116,0.00000695852,0.00002571751,0.000007199277,0.0006401775,0.9987,0.000007697063,0.0003174346,0.000002333833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933299,0.0007303363,0.004871993,0.00002594144,0.00001400349,0.00001705303,0.00008889412,0.00006614038,0.0008558314],"genre_scores_gemma":[0.9942841,0.0003812036,0.003888391,0.00001616272,0.000003186518,0.00001827163,0.0001916584,0.00001532516,0.001201662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006834398,"threshold_uncertainty_score":0.002088606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02405688534885602,"score_gpt":0.2579750097008187,"score_spread":0.2339181243519626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}