{"id":"W2334376408","doi":"10.1158/0008-5472.sabcs11-p1-01-09","title":"P1-01-09: A Focused Immune Response Targeting the Homotypic Binding Domain of the Carcinoembryonic Antigen Blocks the Establishment of Tumor Foci In Vivo.","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Carcinoembryonic antigen; Metastasis; ELISPOT; Cancer research; Immune system; Antigen; Cancer; Medicine; Immunology; T cell; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002519027,0.0007164109,0.0003774139,0.0003004072,0.000156257,0.0002561185,0.0004516117,0.0008084787,0.002190521],"category_scores_gemma":[0.0002072267,0.0002157844,0.0003858257,0.0001152032,0.000343044,0.0002116853,0.0001679898,0.001815865,0.0006179811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000341545,"about_ca_system_score_gemma":0.0003376475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000561505,"about_ca_topic_score_gemma":0.0005107009,"domain_scores_codex":[0.9997701,0.00003921123,0.00001367258,0.00005111938,0.00003807248,0.00008785616],"domain_scores_gemma":[0.9997531,0.00007778839,0.00005120585,0.00002610425,0.00001853789,0.00007316112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009148472,0.0009676439,0.0001076694,0.00006006235,0.00001222494,0.00007262279,0.00001228298,0.0001458692,0.9957744,0.0001118341,0.0001598492,0.001660633],"study_design_scores_gemma":[0.0004974012,0.0108636,0.003626667,0.00002192284,0.00004247539,0.0005372898,0.00001920118,0.001723133,0.9807816,0.00006479416,0.001815053,0.000006972549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945371,0.0006415247,0.001905863,0.0001749232,0.00007505125,0.0001348967,0.0003541521,0.0001083654,0.002068154],"genre_scores_gemma":[0.9911724,0.000540378,0.002730987,0.0002031258,0.00004762277,0.0001925972,0.001505441,0.00003447225,0.003573031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002190521,"threshold_uncertainty_score":0.007328033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06880871459884243,"score_gpt":0.3540303283610619,"score_spread":0.2852216137622194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}