{"id":"W2334414788","doi":"10.2533/chimia.2011.24","title":"Organic Chemistry and Immunochemical Strategies in the Design of Potent Carbohydrate-based Vaccines","year":2011,"lang":"en","type":"review","venue":"CHIMIA International Journal for Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Immunogenicity; Antigen; Immune system; Carbohydrate; Chemistry; Microbiology; Immunology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007013458,0.0012197,0.0007941899,0.001770167,0.000434038,0.0009961786,0.0009242438,0.001193432,0.002193667],"category_scores_gemma":[0.0003377395,0.0006825133,0.000476137,0.002319315,0.0009300497,0.001662251,0.0008747614,0.002227679,0.002966837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001304185,"about_ca_system_score_gemma":0.0006662815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007235431,"about_ca_topic_score_gemma":0.001160955,"domain_scores_codex":[0.9997379,0.00004790134,0.00001772165,0.00005085226,0.0001044884,0.00004104904],"domain_scores_gemma":[0.9999026,0.00003653943,0.00001697452,0.000007280069,0.00002320867,0.00001335605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001249427,0.0004029435,0.000188918,0.01847529,0.00009641897,0.0008926797,0.0002321202,0.005741574,0.06343579,0.07375496,0.01985634,0.816798],"study_design_scores_gemma":[0.00003160293,0.0002440138,0.0003278564,0.001004054,0.00004167471,0.001151677,0.00006201418,0.0007955212,0.02486388,0.01020309,0.9612259,0.00004876712],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001572743,0.9849899,0.00476,0.0004100724,0.0004950514,0.00003979138,0.00003730863,0.00004131331,0.007653888],"genre_scores_gemma":[0.008790123,0.9831965,0.003678957,0.0002792155,0.0002871254,0.00004484022,0.00004730934,0.000007425926,0.003668443],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002193667,"threshold_uncertainty_score":0.009462535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0401961084868329,"score_gpt":0.338960774861005,"score_spread":0.298764666374172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}