{"id":"W2334495433","doi":"10.1158/0008-5472.sabcs-09-4078","title":"High Frequency of BRCA1 Founder Mutations in the Bahamas.","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Founder effect; Breast cancer; Ovarian cancer; Mutation; Population; Genetics; Family history; Cancer; Demography; Medicine; Biology; Internal medicine; Genotype; Haplotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002981699,0.0002267623,0.0002315067,0.0009034115,0.0005096722,0.0005017861,0.0002145254,0.0002746829,0.001827494],"category_scores_gemma":[0.0008408477,0.0001684356,0.0001441609,0.0005862337,0.0002239416,0.0001911052,0.0002691654,0.0001878741,0.0001964739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004576427,"about_ca_system_score_gemma":0.0001817249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01659857,"about_ca_topic_score_gemma":0.01674053,"domain_scores_codex":[0.9997509,0.00005382922,0.000024434,0.00004848034,0.00006462279,0.00005776553],"domain_scores_gemma":[0.9997372,0.00004623369,0.0001055452,0.00002052211,0.00003329034,0.00005720152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004695641,0.00002128273,0.9954458,0.000009861587,0.00001686048,0.0004052137,0.0004875517,0.0000102935,0.001443379,0.00002162403,0.0001131786,0.001977938],"study_design_scores_gemma":[0.000006912848,0.00007295169,0.9969386,0.000006863253,0.00001708071,0.001439763,0.0007448524,0.00007184548,0.0002036324,0.00002042718,0.0004737354,0.000003492773],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993056,0.0002653937,0.00002384412,0.00002914964,0.000003368965,0.000003950004,0.0001401774,0.000002755665,0.0002257171],"genre_scores_gemma":[0.9996421,0.00009648687,0.00002834567,0.00003013027,0.000006069015,0.000003332413,0.0001024763,8.172794e-7,0.00009026156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01659857,"threshold_uncertainty_score":0.03300393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06036859716792139,"score_gpt":0.4092909153499343,"score_spread":0.348922318182013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}