{"id":"W2334513168","doi":"10.1101/cshperspect.a026278","title":"p53 and Medulloblastoma","year":2015,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Medicine","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; Alex's Lemonade Stand Foundation for Childhood Cancer; Canadian Institutes of Health Research; Alberta Innovates; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Ministério da Ciência, Tecnologia e Inovação","keywords":"Medulloblastoma; Sonic hedgehog; Biology; Hedgehog; Cancer research; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003924029,0.0006199057,0.0007052604,0.001923466,0.0003158937,0.0007405024,0.0005318971,0.001041118,0.002730309],"category_scores_gemma":[0.0005536088,0.0002073494,0.0003158651,0.001342075,0.0005117218,0.001106684,0.000693266,0.0017227,0.002036882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007744022,"about_ca_system_score_gemma":0.000939999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001421447,"about_ca_topic_score_gemma":0.00242666,"domain_scores_codex":[0.9998621,0.00001742939,0.00001604673,0.00002491019,0.00006203318,0.00001748013],"domain_scores_gemma":[0.9998411,0.00005982919,0.00002349115,0.000005234901,0.00004591741,0.0000244567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007014279,0.00004158598,0.0003709807,0.006813246,0.00004735099,0.0005141032,0.00007262463,0.0002865118,0.002680273,0.005869768,0.04323121,0.9400021],"study_design_scores_gemma":[0.000008434454,0.00004440088,0.0008160851,0.001400759,0.00003051503,0.002029276,0.00003940196,0.00005014284,0.0005418754,0.002787287,0.9922407,0.00001121847],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001078549,0.9982355,0.00006803661,0.0002805171,0.0001852422,0.000001791524,0.000008509188,0.000006862619,0.001105706],"genre_scores_gemma":[0.0009860152,0.9976634,0.00009343932,0.0001967494,0.0002063403,0.000002594643,0.00002135422,0.000001294536,0.0008288487],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002730309,"threshold_uncertainty_score":0.009133816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05702940369836166,"score_gpt":0.3539287236585644,"score_spread":0.2968993199602027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}