{"id":"W2334513168","doi":"10.1101/cshperspect.a026278","title":"p53 and Medulloblastoma","year":2015,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Medicine","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; Alex's Lemonade Stand Foundation for Childhood Cancer; Canadian Institutes of Health Research; Alberta Innovates; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Ministério da Ciência, Tecnologia e Inovação","keywords":"Medulloblastoma; Sonic hedgehog; Biology; Hedgehog; Cancer research; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007025067,0.0004478012,0.001338846,0.0002383424,0.00005574935,0.00001185809,0.0002858776,0.0003117677,0.000008885495],"category_scores_gemma":[0.0009095495,0.0003654954,0.0001103985,0.0002395285,0.00047011,0.000002634111,0.0002870847,0.000366852,0.000009026566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001490734,"about_ca_system_score_gemma":0.0002308786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000294544,"about_ca_topic_score_gemma":0.00002066943,"domain_scores_codex":[0.9980751,0.0001543497,0.0004217573,0.0007787179,0.0002329533,0.0003371505],"domain_scores_gemma":[0.9989874,0.00005853003,0.000171995,0.0004870741,0.0001358677,0.0001590774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005032559,0.001664822,0.001526527,0.08104245,0.008148336,0.002053898,0.0181959,0.00002422691,0.03605838,0.0545685,0.02984614,0.7663676],"study_design_scores_gemma":[0.0004994748,0.0002946299,0.00006462453,0.005660053,0.0002083404,0.000007456183,0.000532847,0.00000199912,0.00005554756,0.000007817197,0.992299,0.0003681978],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005960109,0.9976783,0.00004636348,0.00007686295,0.0002625959,0.0004860075,0.000009846673,0.0000261176,0.0008178953],"genre_scores_gemma":[0.001965761,0.9963849,0.0002320863,0.00003461982,0.0009872972,0.0001009782,0.00000411329,0.00007430358,0.0002159034],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9624529,"threshold_uncertainty_score":0.9998797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05702940369836166,"score_gpt":0.3539287236585644,"score_spread":0.2968993199602027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}