{"id":"W2334770527","doi":"10.1021/pr501148q","title":"Yeast Mitochondrial Protein–Protein Interactions Reveal Diverse Complexes and Disease-Relevant Functional Relationships","year":2014,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Regina; University of Toronto","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"Crosstalk; Mitochondrion; Biology; Computational biology; Endoplasmic reticulum; Protein–protein interaction; Function (biology); mitochondrial fusion; Immunoprecipitation; Genetics; Mitochondrial DNA; DNAJA3; Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001389862,0.0001314067,0.0001862813,0.000269571,0.0004028993,0.00006845152,0.0001724566,0.0001234256,0.0001772587],"category_scores_gemma":[0.00323861,0.0001114971,0.0001222982,0.000170989,0.0002417425,0.0000251559,0.0001513865,0.000798931,0.00005216012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000388769,"about_ca_system_score_gemma":0.0002671152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001067563,"about_ca_topic_score_gemma":0.0000199221,"domain_scores_codex":[0.9975072,0.001019456,0.0004046888,0.0002737475,0.0005118504,0.0002831295],"domain_scores_gemma":[0.9984109,0.00007221124,0.0001995507,0.0002519538,0.0006691453,0.0003961961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00148905,0.00009399282,0.0008089078,0.0000370156,0.00004045075,0.00001078312,0.00003495883,0.00001679974,0.9854882,0.001266205,0.01023851,0.0004751049],"study_design_scores_gemma":[0.009942546,0.006899916,0.05153859,0.0008314265,0.0001411066,0.00117268,0.0009254577,0.0005990358,0.1925733,0.03330906,0.700923,0.00114382],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9674449,0.0002243378,0.02708882,0.002662919,0.0007590153,0.001013653,0.00003392925,0.000009784804,0.0007626311],"genre_scores_gemma":[0.9808024,0.00002128532,0.0078777,0.00005087718,0.003370818,0.00009540577,0.00003698461,0.00002644483,0.007718073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7929149,"threshold_uncertainty_score":0.4546718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08001507990360375,"score_gpt":0.3314267305240541,"score_spread":0.2514116506204503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}