{"id":"W2334897935","doi":"10.1385/ir:35:1:137","title":"Approaches to studying costimulation of human antiviral T cell responses","year":2006,"lang":"en","type":"review","venue":"Immunologic Research","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"CD28; Immunology; CD8; T cell; Biology; Virology; Viral vector; Recombinant DNA; Antigen-presenting cell; Antigen; Cell biology; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.003331388,0.0007445526,0.002702567,0.001969526,0.0008361891,0.00006683497,0.001860044,0.001796138,0.0002686595],"category_scores_gemma":[0.0004326759,0.0005839258,0.0006144713,0.001470114,0.001387936,0.0001103466,0.001376105,0.002762455,0.00238398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000297134,"about_ca_system_score_gemma":0.0004435274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004734635,"about_ca_topic_score_gemma":0.00001532125,"domain_scores_codex":[0.9898053,0.005734854,0.001565738,0.001182837,0.0002365811,0.001474653],"domain_scores_gemma":[0.9952294,0.002377298,0.0005915382,0.001474743,0.0002949594,0.00003209843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003945178,0.001650771,0.0001096643,0.004556682,0.0007925086,0.00005313574,0.0003580772,0.000004801749,0.3960307,0.001015835,0.004344917,0.5906884],"study_design_scores_gemma":[0.001070448,0.002161191,0.0001024733,0.002173779,0.0002551275,0.00004935079,0.0003372408,4.034015e-7,0.0217877,0.0002057093,0.9711367,0.0007198183],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01787941,0.9704775,0.00001279457,0.00003818445,0.0004847188,0.002473083,0.0001065427,0.0001310947,0.008396655],"genre_scores_gemma":[0.1434393,0.8250741,0.00008320892,0.000006135005,0.00006807326,0.000411278,0.0006910985,0.0001002171,0.03012661],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9667919,"threshold_uncertainty_score":0.9996612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4443411910013474,"score_gpt":0.4243844078791005,"score_spread":0.01995678312224691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}