{"id":"W2335056292","doi":"10.1242/dev.134270","title":"G2-phase arrest prevents bristle progenitor self-renewal and synchronizes cell divisions with cell fate differentiation","year":2016,"lang":"en","type":"article","venue":"Development","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Biology; Bristle; Cell biology; Progenitor cell; Progenitor; Cell fate determination; Cellular differentiation; Cell; Stem cell; Genetics; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008038526,0.0002680856,0.0002126127,0.0002242797,0.0001582653,0.0002525896,0.0002017801,0.0002127031,0.001301852],"category_scores_gemma":[0.00008690701,0.000146701,0.0001800826,0.0001233522,0.0002230579,0.0002009842,0.000238943,0.0004168144,0.0003626093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002914106,"about_ca_system_score_gemma":0.0003606169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007985606,"about_ca_topic_score_gemma":0.00174769,"domain_scores_codex":[0.9998969,0.00001315194,0.000009107745,0.0000231641,0.00002385996,0.00003390304],"domain_scores_gemma":[0.9999352,0.00001067944,0.00001921368,0.00001156465,0.000005523405,0.00001791291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008663439,0.00002814617,0.0002398206,0.00002417221,0.000002947169,0.00003651612,0.000009325665,0.00007673575,0.9981141,0.0002336496,0.00006356941,0.001084441],"study_design_scores_gemma":[0.00001460538,0.0001557555,0.002953576,0.000005081361,0.00000601558,0.00009624111,0.00001289261,0.0007847015,0.9928772,0.00005537171,0.003035692,0.000002848608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945658,0.001190512,0.001710983,0.0000777876,0.00003164498,0.00002762534,0.0002743241,0.00009563276,0.002025621],"genre_scores_gemma":[0.9939463,0.0007690965,0.001291825,0.00004974821,0.000008513854,0.00003585537,0.0004169329,0.00003215553,0.003449637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001301852,"threshold_uncertainty_score":0.004355133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006078653993006525,"score_gpt":0.2164026944058084,"score_spread":0.2103240404128019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}