{"id":"W2335056292","doi":"10.1242/dev.134270","title":"G2-phase arrest prevents bristle progenitor self-renewal and synchronizes cell divisions with cell fate differentiation","year":2016,"lang":"en","type":"article","venue":"Development","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Biology; Bristle; Cell biology; Progenitor cell; Progenitor; Cell fate determination; Cellular differentiation; Cell; Stem cell; Genetics; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008616477,0.0001710801,0.0001125648,0.00003074523,0.0001363742,0.00002889877,0.00009668202,0.00008402101,0.00001629263],"category_scores_gemma":[0.000007639539,0.0001130022,0.00002599717,0.00003995987,0.00002957211,0.000004584188,0.00007992299,0.00003657723,0.00002146194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002756988,"about_ca_system_score_gemma":0.0001616148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003287844,"about_ca_topic_score_gemma":0.00001344799,"domain_scores_codex":[0.9990599,0.00003972829,0.0001755283,0.0003431127,0.0001481497,0.0002336208],"domain_scores_gemma":[0.9995645,0.00000837284,0.00008150931,0.0001715415,0.00004948305,0.0001245785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000426843,0.0003178404,0.005129361,0.00004017254,0.00004856938,0.00000492965,0.0002152131,0.000001152221,0.9875121,0.000002234882,0.00009512767,0.006590625],"study_design_scores_gemma":[0.00182591,0.0002597267,0.002727609,0.0000558406,0.00002480331,0.000003471785,0.00002156503,0.000007314577,0.9823761,0.000009670057,0.01244148,0.0002465298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929277,0.0002817223,0.00621895,0.00003080735,0.0001047201,0.0002205556,0.00001819943,0.00002833566,0.0001689623],"genre_scores_gemma":[0.992989,0.00008628963,0.005170436,0.00001843644,0.00008531258,0.00005430273,0.0001097165,0.00002276772,0.001463755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01234635,"threshold_uncertainty_score":0.4608094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006078653993006525,"score_gpt":0.2164026944058084,"score_spread":0.2103240404128019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}