{"id":"W2335094569","doi":"10.1016/j.jalz.2016.02.006","title":"Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease","year":2016,"lang":"en","type":"review","venue":"Alzheimer s & Dementia","topic":"Stroke Rehabilitation and Recovery","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute on Aging; University of California, San Francisco; University of California, San Diego; Genentech; National Institutes of Health; IXICO; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of California, Los Angeles; European Medicines Agency; Servier; Eisai; Northern California Institute for Research and Education; Illinois Department of Public Health; Rush University; University of Washington; Alzheimer’s Research UK; Pfizer; Biogen; BioClinica; McGill University; National Institute of Mental Health; Takeda Pharmaceuticals U.S.A.; European Federation of Pharmaceutical Industries and Associations; Medpace; Sanofi; Synarc; University of Southern California; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Alzheimer's Association; BrightFocus Foundation; Eli Lilly and Company; Bristol-Myers Squibb; Novartis Pharmaceuticals Corporation","keywords":"Resilience (materials science); Cognitive decline; Estimation; Cognition; Disease; Alzheimer's disease; Cognitive psychology; Psychology; Cognitive aging; Gerontology; Medicine; Dementia; Neuroscience; Pathology; Economics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003078216,0.0003226299,0.001125934,0.0003941907,0.00003615661,0.00001387343,0.000100231,0.0001723688,0.0001901885],"category_scores_gemma":[0.0004676911,0.0002299774,0.000301954,0.000266103,0.0002486569,0.0001101973,0.0001052399,0.0001729735,0.00005896642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009230755,"about_ca_system_score_gemma":0.000310099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001712825,"about_ca_topic_score_gemma":0.000004055846,"domain_scores_codex":[0.9979833,0.0001692533,0.0008426024,0.0004619523,0.0003060171,0.0002368513],"domain_scores_gemma":[0.9981378,0.0008455106,0.0004073965,0.0002884963,0.000107026,0.0002138198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008143257,0.0001107314,0.001492638,0.0006934113,0.003557485,0.0000139583,0.00005099558,6.160711e-7,6.848907e-7,0.00003701052,0.00007870513,0.9938824],"study_design_scores_gemma":[0.006048999,0.0008402762,0.07704857,0.125612,0.3378026,0.00008541875,0.0001632779,0.0003787429,0.00009331183,0.0003461105,0.4500602,0.001520447],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006225265,0.9972876,0.0001300952,0.00009364455,0.0001663635,0.001360364,0.00007839622,0.00002387181,0.0002371157],"genre_scores_gemma":[0.07118733,0.9277725,0.0005809271,0.00007012591,0.00006669587,0.0001201727,0.0001522998,0.00003999417,0.00001001765],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9923619,"threshold_uncertainty_score":0.9378207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03291330977321506,"score_gpt":0.3484717326737906,"score_spread":0.3155584229005756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}