{"id":"W2335205195","doi":"10.1021/es504331n","title":"The Antidepressant Venlafaxine Disrupts Brain Monoamine Levels and Neuroendocrine Responses to Stress in Rainbow Trout","year":2014,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"European Social Fund; Natural Sciences and Engineering Research Council of Canada","keywords":"Venlafaxine; Monoamine neurotransmitter; Rainbow trout; Serotonin; Antidepressant; Endocrinology; Internal medicine; Dopamine; Trout; Reuptake inhibitor; Norepinephrine; Monoaminergic; Psychology; Biology; Medicine; Fish <Actinopterygii>; Fishery; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006035197,0.000234873,0.0002410923,0.0001578752,0.0002024461,0.0001955449,0.0001773182,0.0002627296,0.0006973047],"category_scores_gemma":[0.00008845724,0.0001583375,0.0003012125,0.00009692177,0.0002680105,0.0001591184,0.0002061805,0.0004397792,0.0001047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000600912,"about_ca_system_score_gemma":0.0003919721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006555499,"about_ca_topic_score_gemma":0.01689259,"domain_scores_codex":[0.9999259,0.000006775065,0.000006849438,0.00002096382,0.00001816452,0.00002150884],"domain_scores_gemma":[0.9999402,0.000005389517,0.00002164168,0.000005396224,0.000008779475,0.00001859695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002369746,0.0000257534,0.000984768,0.00001547417,0.000008816118,0.00003473516,0.00002317485,0.00004054319,0.9982044,0.00002004436,0.00001770059,0.0003877757],"study_design_scores_gemma":[0.00008527927,0.004592584,0.1524377,0.00001327172,0.00009714968,0.0002682353,0.000303418,0.001037043,0.8395051,0.0001072017,0.001525059,0.00002789713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992286,0.0001296405,0.0001840358,0.00003985953,0.000009822439,0.000008865493,0.0001538824,0.00001223512,0.0002331359],"genre_scores_gemma":[0.9969804,0.000262505,0.0005224629,0.00007455488,0.000003578589,0.00003254848,0.000282257,0.000007919749,0.001833695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006555499,"threshold_uncertainty_score":0.0130347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005774465816386014,"score_gpt":0.2286463695841952,"score_spread":0.2228719037678092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}