{"id":"W2335219482","doi":"10.1021/bc100397b","title":"Synthesis and Immunogenicity of a Glycopolymer Conjugate","year":2010,"lang":"ca","type":"article","venue":"Bioconjugate Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Trisaccharide; Chemistry; Immunogenicity; Glycopolymer; Conjugate; Epitope; Conjugate vaccine; Hapten; Antigen; Mannan; Biochemistry; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004721944,0.0004650987,0.0004949588,0.00005591435,0.0001705046,0.00008690484,0.0004957969,0.0008719196,0.001652767],"category_scores_gemma":[0.000629867,0.0004790605,0.0002631237,0.0001845097,0.00108945,0.00001168953,0.000482845,0.0005702616,0.0000441626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000170136,"about_ca_system_score_gemma":0.0003620525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001894925,"about_ca_topic_score_gemma":0.00002714732,"domain_scores_codex":[0.997465,0.00007570159,0.0006645519,0.0008297648,0.000358585,0.0006064023],"domain_scores_gemma":[0.9978526,0.00006709289,0.0003267534,0.001055488,0.0003166169,0.0003813992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004685762,0.000166785,0.0009696908,0.0005527241,0.0002287756,0.00001332886,0.0000296733,4.73019e-7,0.9931104,0.0001181349,0.0003496964,0.00399181],"study_design_scores_gemma":[0.001065618,0.0001062469,0.0004340491,0.00007288698,0.00007752026,0.00008924869,0.0001059479,0.00006979589,0.9653132,0.00007452733,0.0321139,0.0004770618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823996,0.003924389,0.00002344036,0.0003356321,0.0002221658,0.0004081039,0.0003853074,0.00001939053,0.01228192],"genre_scores_gemma":[0.9942936,0.001459539,0.000277734,0.00007170971,0.0003679148,0.00006442412,0.0001079829,0.00006279452,0.003294284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03176421,"threshold_uncertainty_score":0.9997661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0070241604260374,"score_gpt":0.2476485391397974,"score_spread":0.24062437871376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}