{"id":"W2335400975","doi":"10.1021/bi3010158","title":"Tandem Affinity Purification in Transgenic Mouse Embryonic Stem Cells Identifies DDOST as a Novel PPP1CC2 Interacting Protein","year":2012,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Embryonic stem cell; Tandem affinity purification; Genetically modified mouse; Transgene; Cell biology; Tandem; Stem cell; Chemistry; Biology; Affinity chromatography; Molecular biology; Computational biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002823817,0.0001956762,0.0001407263,0.00003761967,0.00008525758,0.00005327208,0.0002579592,0.0002390023,0.00004316434],"category_scores_gemma":[0.000042357,0.0002084319,0.0001013612,0.0001386427,0.00005843479,0.00001826298,0.00005570116,0.0001770884,0.00003678353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007654978,"about_ca_system_score_gemma":0.0001307612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003198793,"about_ca_topic_score_gemma":0.00001687919,"domain_scores_codex":[0.9987882,0.00003343853,0.0002957678,0.0003854877,0.0001448956,0.0003522091],"domain_scores_gemma":[0.999143,0.00001095704,0.0001541073,0.0005078168,0.00007066401,0.0001134242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000374784,0.0002143956,0.0006573502,0.00005753497,0.00002398239,2.379556e-7,0.0001062739,0.00001099204,0.9980539,0.00002037446,0.0002825999,0.0005348452],"study_design_scores_gemma":[0.0004092513,0.00002285662,0.000539522,0.00003986564,0.00001231544,0.000006182843,0.0005257698,0.00001816592,0.9948664,0.000003392953,0.003314028,0.0002422738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969873,0.001153926,0.0004863574,0.0001126914,0.0001414407,0.0002773256,0.00003040808,0.00002262764,0.0007879205],"genre_scores_gemma":[0.9922981,0.0001027525,0.0002315153,0.00004339938,0.0002632945,0.0001741895,0.00009558966,0.0000300715,0.006761078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005973157,"threshold_uncertainty_score":0.8499608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02017753072128991,"score_gpt":0.2640159053621356,"score_spread":0.2438383746408457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}