{"id":"W2335432651","doi":"10.1021/bi5013782","title":"Ligand Recognition Specificity of Leukocyte Integrin α<sub>M</sub>β<sub>2</sub> (Mac-1, CD11b/CD18) and Its Functional Consequences","year":2015,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Heart, Lung, and Blood Institute","keywords":"Phage display; Integrin alpha M; Peptide; Integrin; Peptide library; Cell adhesion; Binding selectivity; Binding site; Biology; CD18; Chemistry; Biochemistry; Peptide sequence; Receptor; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001211725,0.0001662561,0.0001208714,0.0001011436,0.00008871708,0.0003304096,0.0001549227,0.0001858954,0.0008354716],"category_scores_gemma":[0.0001824216,0.000101878,0.0001289271,0.00009148457,0.0001686746,0.0001603821,0.0001262033,0.00030358,0.0002695786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002353067,"about_ca_system_score_gemma":0.00009542701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003822359,"about_ca_topic_score_gemma":0.0003279337,"domain_scores_codex":[0.9998583,0.00002583046,0.000007217607,0.0000311185,0.00003887491,0.00003863276],"domain_scores_gemma":[0.9999293,0.00002269071,0.00001475205,0.000005379456,0.000010092,0.00001765616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009319092,0.00001346553,0.001003324,0.00001379243,0.000002269849,0.00005012107,0.00001079748,0.0001262698,0.9963966,0.0001312702,0.00002363329,0.002135274],"study_design_scores_gemma":[0.00001614097,0.0004375692,0.0452743,0.000006791069,0.00002089482,0.001539148,0.00006573163,0.003852494,0.9464346,0.0003518966,0.001986816,0.00001367079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977544,0.0006763164,0.0007939916,0.00003261676,0.000003374429,0.000003083457,0.00003316192,0.000008435384,0.0006947488],"genre_scores_gemma":[0.9983146,0.0003516588,0.0006581757,0.0000593547,0.000005520284,0.000006047981,0.0001390373,0.000004540836,0.0004610226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008354716,"threshold_uncertainty_score":0.002794981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06603466669532845,"score_gpt":0.2814880266249437,"score_spread":0.2154533599296152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}