{"id":"W2335708793","doi":"10.1158/1538-7445.am2011-5074","title":"Abstract 5074: Evaluation of PTEN and TMPRSS2-ERG abnormalities in prostate cancer by FISH and immunohistochemistry to address intra- and inter- tissue heterogeneity and disease progression","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Toronto; Queen's University; University Health Network","funders":"","keywords":"PTEN; Prostate cancer; TMPRSS2; Prostate; Erg; Immunohistochemistry; Tissue microarray; Prostatectomy; Pathology; Cancer; Biology; Fusion gene; Cancer research; Carcinoma; Medicine; Internal medicine; Disease; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003846065,0.0002185325,0.0001876371,0.0009717622,0.0001847759,0.0001442281,0.0001617433,0.0002563428,0.00327487],"category_scores_gemma":[0.0002874589,0.0001405388,0.0001363334,0.0003635036,0.0002196964,0.0002142889,0.0001715995,0.000136914,0.0004300305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003699538,"about_ca_system_score_gemma":0.0001600597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001157264,"about_ca_topic_score_gemma":0.001819337,"domain_scores_codex":[0.9998382,0.00002949782,0.00001485497,0.00004133302,0.00004383914,0.00003212232],"domain_scores_gemma":[0.9998686,0.00004295684,0.00002277985,0.00001486305,0.00003007393,0.00002072638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002863139,0.00003046701,0.03208133,0.0000788634,0.00002237638,0.0003384107,0.0000682638,0.0002205809,0.961418,0.00007220367,0.0001332728,0.005249872],"study_design_scores_gemma":[0.00006158341,0.00107513,0.4679474,0.00001627991,0.0001305821,0.006558707,0.0002870905,0.006093411,0.5136991,0.0002163116,0.003894416,0.0000200236],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937245,0.0004938353,0.003656569,0.00003773097,0.000005284174,0.00005160047,0.0002755361,0.00005904384,0.001695902],"genre_scores_gemma":[0.9932536,0.0002367764,0.004893362,0.00002405469,0.000005176847,0.00007404591,0.000401009,0.00001142399,0.001100435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00327487,"threshold_uncertainty_score":0.01095551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09877131346931951,"score_gpt":0.4575403250542027,"score_spread":0.3587690115848832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}