{"id":"W2335848215","doi":"10.3892/etm.2016.3284","title":"Efficacy of memantine on neuropsychiatric symptoms associated with the severity of behavioral variant frontotemporal dementia: A six-month, open-label, self-controlled clinical trial","year":2016,"lang":"en","type":"article","venue":"Experimental and Therapeutic Medicine","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Memantine; Apathy; Frontotemporal dementia; Disinhibition; Clinical Dementia Rating; Montreal Cognitive Assessment; Depression (economics); Internal medicine; Medicine; Dementia; Psychology; Psychiatry; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002092591,0.001570697,0.002951617,0.0005867293,0.0006184495,0.0006956804,0.001011471,0.002273661,0.002717928],"category_scores_gemma":[0.001416256,0.0005088094,0.001089756,0.0003584826,0.0009961507,0.0009502866,0.000309574,0.001612313,0.0006709817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003618114,"about_ca_system_score_gemma":0.0006002609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003610117,"about_ca_topic_score_gemma":0.0008718029,"domain_scores_codex":[0.9993855,0.0003287325,0.00005679834,0.00008565887,0.0000537541,0.00008950524],"domain_scores_gemma":[0.9990953,0.0002712783,0.0001563252,0.00008300874,0.0000735952,0.0003204152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9115705,0.04235296,0.001419714,0.0007208323,0.0004657318,0.0001459386,0.0001555595,0.000318017,0.01155316,0.00005640444,0.0004406564,0.03080057],"study_design_scores_gemma":[0.7413851,0.2520035,0.004349092,0.0000283783,0.0001618667,0.00007247061,0.00003430692,0.0004633369,0.001014356,0.00006641506,0.0004011407,0.00002008069],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944441,0.002137737,0.0003040063,0.00016788,0.0001750987,0.001673286,0.000301943,0.00008575422,0.0007103003],"genre_scores_gemma":[0.9911747,0.001579549,0.001094944,0.0005044674,0.0004166052,0.003302805,0.0004712168,0.00001332979,0.001442338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002951617,"threshold_uncertainty_score":0.01106679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0800158804627631,"score_gpt":0.3938823969701048,"score_spread":0.3138665165073417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}