{"id":"W2336474906","doi":"10.1177/1756283x15618130","title":"Ustekinumab for the treatment of Crohn’s disease: can it find its niche?","year":2015,"lang":"en","type":"review","venue":"Therapeutic Advances in Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Ustekinumab; Medicine; Crohn's disease; Psoriatic arthritis; Psoriasis; Disease; Vedolizumab; Infliximab; Adalimumab; Immunology; Cohort; Secukinumab; Pharmacotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000568867,0.0005614078,0.001255396,0.001811008,0.0002343598,0.0009072281,0.0007344664,0.001018195,0.00391405],"category_scores_gemma":[0.0008576805,0.0001953688,0.0005396972,0.001671317,0.0003848877,0.001362391,0.0005488139,0.001893045,0.002240845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004049522,"about_ca_system_score_gemma":0.0006707464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006223302,"about_ca_topic_score_gemma":0.00170676,"domain_scores_codex":[0.9998032,0.00003697057,0.00003640874,0.00002689907,0.00007950657,0.00001711682],"domain_scores_gemma":[0.9996986,0.0001453435,0.00004806973,0.000008429226,0.00006917409,0.00003045467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008839479,0.00004094717,0.000135713,0.0122426,0.00008691853,0.0002046849,0.0000432634,0.0001331922,0.0007851712,0.001889544,0.02787431,0.9564752],"study_design_scores_gemma":[0.00003395912,0.00007949203,0.0005922069,0.004738974,0.0001289094,0.001807909,0.00005215139,0.00004513934,0.0002136354,0.001470251,0.9908231,0.00001409218],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006515699,0.9989868,0.00004045882,0.0002940111,0.0001617368,0.000002249026,0.000009019777,0.00000316162,0.0004374826],"genre_scores_gemma":[0.0004226013,0.9986426,0.0000841088,0.0002924564,0.0001759986,0.000002693808,0.00001679533,0.000001140273,0.0003615295],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00391405,"threshold_uncertainty_score":0.01309383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03938787289550029,"score_gpt":0.3510862701215244,"score_spread":0.3116983972260242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}