{"id":"W2336577938","doi":"10.1158/2326-6074.tumimm14-b88","title":"Abstract B88: Combination therapy of reovirus and checkpoint inhibition","year":2015,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada); Institute of Cancer Research","funders":"","keywords":"Oncolytic virus; Immune system; Immune checkpoint; Cancer research; Immunotherapy; Antigen; Immunology; Innate immune system; Medicine; Acquired immune system; Biology; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001649457,0.0001121656,0.0001582492,0.0001840068,0.00009313796,0.00001903231,0.0001987211,0.000218545,0.00007038433],"category_scores_gemma":[0.0001623529,0.0001062394,0.00003966405,0.000233836,0.0006786686,0.000008844028,0.0001639235,0.0003318701,0.00001697375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007282625,"about_ca_system_score_gemma":0.0005060722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002802892,"about_ca_topic_score_gemma":0.0001422701,"domain_scores_codex":[0.9984467,0.0003009913,0.0002172893,0.0003270774,0.0003332051,0.0003747217],"domain_scores_gemma":[0.9987088,0.00003618293,0.00006596497,0.000388367,0.0007091173,0.0000914991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004023108,0.0001133492,0.001370585,0.00001291946,0.0000859376,0.000002930807,0.0001945426,0.000006773024,0.9594488,0.00008887162,0.0008052617,0.03384693],"study_design_scores_gemma":[0.002301496,0.003451081,0.00796834,0.00001883234,0.000001451694,0.000006613227,0.0002431351,0.00001062583,0.978813,0.0009108525,0.006165904,0.0001086853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768418,0.0207102,0.000009852892,0.0007241663,0.00008515982,0.0003319446,0.00001411002,0.000008942709,0.001273811],"genre_scores_gemma":[0.9875504,0.01172012,0.00002369352,0.0000533996,0.00009255504,0.0001294282,0.00005161487,0.00002387818,0.0003548653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03373824,"threshold_uncertainty_score":0.4332318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09997797559208603,"score_gpt":0.4035108601861042,"score_spread":0.3035328845940182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}