{"id":"W2336577938","doi":"10.1158/2326-6074.tumimm14-b88","title":"Abstract B88: Combination therapy of reovirus and checkpoint inhibition","year":2015,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada); Institute of Cancer Research","funders":"","keywords":"Oncolytic virus; Immune system; Immune checkpoint; Cancer research; Immunotherapy; Antigen; Immunology; Innate immune system; Medicine; Acquired immune system; Biology; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001338095,0.0005934131,0.0005806828,0.0003961843,0.00009336638,0.0003326769,0.0004121894,0.0003785121,0.001833778],"category_scores_gemma":[0.00007981681,0.0001319746,0.0003608225,0.0001829345,0.0001443954,0.0002140373,0.0002209322,0.00099844,0.0004225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002123935,"about_ca_system_score_gemma":0.0002561231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005595944,"about_ca_topic_score_gemma":0.0009190194,"domain_scores_codex":[0.999882,0.00001989283,0.000007522335,0.00002428198,0.00002910799,0.00003725689],"domain_scores_gemma":[0.9999489,0.0000067314,0.00001253085,0.000009520257,0.000005012705,0.0000173776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002297494,0.001483447,0.0003947596,0.0002323079,0.00005306761,0.0001041998,0.00003127408,0.001179527,0.9540647,0.0004017064,0.0005485045,0.03920893],"study_design_scores_gemma":[0.0009887217,0.02028281,0.002297753,0.00004918862,0.0001360231,0.0006586351,0.00002210851,0.002500061,0.963901,0.0001081804,0.009035633,0.00001985563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828571,0.005969766,0.005454422,0.0002314846,0.0001667329,0.0002959619,0.0004377212,0.0002279839,0.004358765],"genre_scores_gemma":[0.9892192,0.00193648,0.004408684,0.00006546312,0.00003635546,0.0001617213,0.0003783346,0.00003217008,0.003761577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001833778,"threshold_uncertainty_score":0.00613457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09997797559208603,"score_gpt":0.4035108601861042,"score_spread":0.3035328845940182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}