{"id":"W2336694595","doi":"10.1177/2055217316634111","title":"Delayed-release dimethyl fumarate and disability assessed by the Multiple Sclerosis Functional Composite: Integrated analysis of DEFINE and CONFIRM","year":2016,"lang":"en","type":"article","venue":"Multiple Sclerosis Journal - Experimental Translational and Clinical","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; NeuroRx Research (Canada); Montreal Neurological Institute and Hospital","funders":"Marshall Space Flight Center; Biogen","keywords":"Dimethyl fumarate; Multiple sclerosis; Composite number; Psychology; Physical medicine and rehabilitation; Medicine; Chemistry; Materials science; Immunology; Composite material","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002199184,0.0005718975,0.0010702,0.0007273483,0.0001810726,0.0003348064,0.0003070769,0.0002398044,0.0007539949],"category_scores_gemma":[0.001459486,0.0001433117,0.0007746872,0.0005362275,0.00016745,0.0003023738,0.0003431171,0.0004088754,0.0001224447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003663694,"about_ca_system_score_gemma":0.0003476875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001391422,"about_ca_topic_score_gemma":0.003675925,"domain_scores_codex":[0.9992673,0.0003066252,0.00005897948,0.00006963871,0.0002369059,0.00006051303],"domain_scores_gemma":[0.998718,0.0002178712,0.0006746146,0.00006546111,0.0001862642,0.0001377819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.1755933,0.003593941,0.6325959,0.0009836525,0.006105541,0.0001619132,0.0002883335,0.002724051,0.03315018,0.0002959248,0.001335503,0.1431718],"study_design_scores_gemma":[0.00333116,0.02980914,0.9517879,0.00004399568,0.001682055,0.0004191126,0.00005388377,0.001544444,0.009302213,0.00009992711,0.001886136,0.00003995718],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938968,0.002390334,0.0008330946,0.00004157323,0.00001068966,0.000285304,0.001137412,0.00003681024,0.00136816],"genre_scores_gemma":[0.9963069,0.000412749,0.001286799,0.00003126252,0.00001123136,0.0001735233,0.001215113,0.000006961217,0.0005554692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002199184,"threshold_uncertainty_score":0.01163054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1598994560791916,"score_gpt":0.3631188300911166,"score_spread":0.2032193740119249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}