{"id":"W2336852147","doi":"10.1200/jco.2004.22.90140.2","title":"Concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) for newly diagnosed glioblastoma multiforme (GBM). Conclusive results of a randomized phase III trial by the EORTC Brain &amp; RT Groups and NCIC Clinical Trials Group","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Calgary; Western University","funders":"","keywords":"Temozolomide; Medicine; Glioblastoma; Concomitant; Radiation therapy; Oncology; Adjuvant; Internal medicine; Clinical trial; Phases of clinical research; Randomized controlled trial; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009227853,0.0006670376,0.001440019,0.000292711,0.0002633671,0.00048635,0.0005663888,0.0006753828,0.002942203],"category_scores_gemma":[0.001299048,0.0003847872,0.0008156364,0.0004362175,0.0005146754,0.0007899733,0.0003992991,0.001766022,0.0003894783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006923965,"about_ca_system_score_gemma":0.001536488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001758789,"about_ca_topic_score_gemma":0.008753076,"domain_scores_codex":[0.9995694,0.0002143571,0.00003632841,0.00006587622,0.00004406175,0.00006996849],"domain_scores_gemma":[0.9993821,0.0001340381,0.0001249624,0.00004607491,0.00002485799,0.0002878482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8950619,0.01113495,0.004891919,0.0007721534,0.001221456,0.00008299056,0.00008679125,0.0007473377,0.006479087,0.0002236337,0.001362702,0.07793503],"study_design_scores_gemma":[0.5786353,0.3783911,0.03068296,0.0001492052,0.002197364,0.0003163165,0.0000729638,0.001229673,0.002914458,0.0003754385,0.004998028,0.00003716058],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898309,0.006619208,0.0003261575,0.0003880033,0.0002880919,0.0006427045,0.000505216,0.00003469613,0.001365005],"genre_scores_gemma":[0.9901854,0.005098823,0.0009738344,0.0003710998,0.0003304611,0.0006335629,0.0009441464,0.00001001094,0.001452582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002942203,"threshold_uncertainty_score":0.009842634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.108825692048176,"score_gpt":0.4899773576361529,"score_spread":0.3811516655879769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}