{"id":"W2337288646","doi":"10.71781/27721","title":"Activation de la voie oncogénique mTOR par les formes mutées de l'isocitrate déshydrogénase 1/2 retrouvées chez les gliomes","year":2015,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Chemistry; Molecular biology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158963,0.000404251,0.0003227988,0.000506784,0.0002815851,0.0005905444,0.0002108623,0.000327884,0.002589933],"category_scores_gemma":[0.0003248069,0.0001773505,0.0004363864,0.0003812567,0.0003473872,0.0002726988,0.0003149705,0.0005410482,0.000670764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000413416,"about_ca_system_score_gemma":0.0002680963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001090841,"about_ca_topic_score_gemma":0.001326622,"domain_scores_codex":[0.999808,0.00001559973,0.00001494068,0.00005529431,0.00006795695,0.00003825609],"domain_scores_gemma":[0.9998621,0.00002224632,0.00004838171,0.00002049933,0.00002450381,0.00002224641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002044802,0.00003384179,0.006232667,0.0001410282,0.00005033668,0.0005405637,0.00009230948,0.0003106796,0.9738545,0.0007381861,0.0002598448,0.01754164],"study_design_scores_gemma":[0.00004190844,0.000406448,0.05370697,0.00002164136,0.0001289651,0.00449284,0.0002097357,0.001004547,0.9140526,0.0005105432,0.02540094,0.0000227564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840577,0.005072059,0.004518857,0.0002837733,0.00009346246,0.00003701233,0.0008114079,0.0002307643,0.004894895],"genre_scores_gemma":[0.9865429,0.002591939,0.001499004,0.0001273845,0.00002108666,0.00005720539,0.0009507991,0.00005296894,0.008156719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002589933,"threshold_uncertainty_score":0.008664191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005415146284100543,"score_gpt":0.2019835196192845,"score_spread":0.196568373335184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}