{"id":"W2337430744","doi":"10.1158/1535-7163.mct-15-0695","title":"Strategic Combinations: The Future of Oncolytic Virotherapy with Reovirus","year":2016,"lang":"en","type":"review","venue":"Molecular Cancer Therapeutics","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Guizhou University; National Natural Science Foundation of China","keywords":"Oncolytic virus; Virotherapy; Cancer research; Cancer; Immune system; Radiation therapy; Immunotherapy; Cancer cell; Medicine; Biology; Immunology; Virology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003552277,0.0006058223,0.0008935268,0.0001256612,0.0001337047,0.00004987094,0.001075751,0.0004861167,0.00009006547],"category_scores_gemma":[0.000002735022,0.0003305632,0.0004831308,0.0004342117,0.0004008551,0.000004018696,0.00009096879,0.0004086789,0.00001619221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001232559,"about_ca_system_score_gemma":0.001561963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001076387,"about_ca_topic_score_gemma":0.0001278919,"domain_scores_codex":[0.9972526,0.0005798873,0.0005206834,0.000611934,0.0005516247,0.0004833039],"domain_scores_gemma":[0.9976939,0.00004886042,0.0004711782,0.00144344,0.0002534062,0.00008924177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005242775,0.000152287,0.000001854846,0.001033019,0.002017336,0.00001237498,0.00002888296,0.00001065453,0.0123404,0.0005985937,0.00007676303,0.9832035],"study_design_scores_gemma":[0.001022603,0.002267869,4.550531e-7,0.001541077,0.0004639871,0.00002258508,0.00003257377,0.000002740707,0.01077105,0.0002940427,0.9830892,0.0004917883],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006150658,0.9965605,0.0002776759,0.0003406428,0.0001828234,0.001422342,0.0001767808,0.00001725251,0.0004069784],"genre_scores_gemma":[0.0006655324,0.9967945,0.00005457016,0.0006322867,0.0004133727,0.0005933669,0.00009125643,0.0002081821,0.0005469326],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9830124,"threshold_uncertainty_score":0.9999146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05086805946299626,"score_gpt":0.3713914075100794,"score_spread":0.3205233480470831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}