{"id":"W2338344824","doi":"10.1038/ncomms11310","title":"Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Nagoya City University; Deutsche Forschungsgemeinschaft; Boehringer Ingelheim Fonds; Max-Planck-Gesellschaft; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Chromatin; Heterochromatin protein 1; Heterochromatin; Chromodomain; Cell biology; Histone; Chromatin remodeling; Non-histone protein; Histone code; Histone H3; Biophysics; Biology; Nucleosome; Genetics; Chemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001082834,0.0001087855,0.000121834,0.0000525882,0.0001090557,0.00001945794,0.0003647545,0.0001356896,0.000004899949],"category_scores_gemma":[0.0001877276,0.00009106545,0.00003556068,0.0001005331,0.0001757648,0.000008171171,0.0002775855,0.0001223644,0.000002034666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001732137,"about_ca_system_score_gemma":0.00005399014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009118521,"about_ca_topic_score_gemma":0.0002190965,"domain_scores_codex":[0.9993489,0.00005956177,0.0002165081,0.000173132,0.00007444047,0.0001274756],"domain_scores_gemma":[0.9987598,0.0000970538,0.0001540359,0.0008260502,0.0001186642,0.00004437346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001320938,0.00003949184,0.001692426,0.00001816128,0.00003703236,1.329454e-7,0.00005304653,0.00004804749,0.9914448,0.0002935866,0.0001256122,0.006234398],"study_design_scores_gemma":[0.005284999,0.000876935,0.3215699,0.0005493045,0.00026808,0.0001256319,0.0002483634,0.1278275,0.5142884,0.004909398,0.02224559,0.001805884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760087,0.002541906,0.02037388,0.0005071884,0.00007188194,0.0001460248,0.0001046541,0.00001945585,0.0002263115],"genre_scores_gemma":[0.9923307,0.001170864,0.005987528,0.00005567535,0.000009565514,0.0000139223,0.0002227049,0.00001988064,0.0001891153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4771564,"threshold_uncertainty_score":0.3713541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005326283764169932,"score_gpt":0.2417670998554512,"score_spread":0.2364408160912813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}