{"id":"W2338344824","doi":"10.1038/ncomms11310","title":"Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Nagoya City University; Deutsche Forschungsgemeinschaft; Boehringer Ingelheim Fonds; Max-Planck-Gesellschaft; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Chromatin; Heterochromatin protein 1; Heterochromatin; Chromodomain; Cell biology; Histone; Chromatin remodeling; Non-histone protein; Histone code; Histone H3; Biophysics; Biology; Nucleosome; Genetics; Chemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000844855,0.0001563737,0.0001209804,0.00008151342,0.0001575554,0.0002448817,0.0001518849,0.0001667908,0.0009844712],"category_scores_gemma":[0.0001072717,0.0001452383,0.0001274801,0.00007560533,0.0002450209,0.0002174018,0.0002525852,0.0003156514,0.0002651969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000138358,"about_ca_system_score_gemma":0.00008194706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002380841,"about_ca_topic_score_gemma":0.0002484387,"domain_scores_codex":[0.9999338,0.000007431879,0.000002393513,0.00002770391,0.00001384301,0.00001486306],"domain_scores_gemma":[0.9999442,0.000008613166,0.00001563291,0.000009259597,0.000005462553,0.00001682755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003185069,0.000004907528,0.0003458213,0.00001047915,0.00000384139,0.00002582171,0.00001528312,0.00006853235,0.9987009,0.00009969915,0.00002069408,0.0006721794],"study_design_scores_gemma":[0.00001450252,0.0000982258,0.01635489,0.000005446089,0.00001040922,0.0004614311,0.00006279632,0.002471331,0.9777218,0.0004067714,0.002385632,0.000006876346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934275,0.0004842527,0.005185265,0.00004775425,0.000008182295,0.000005624951,0.00007247153,0.0000440397,0.0007248773],"genre_scores_gemma":[0.9986693,0.0001494232,0.0006577928,0.00002519921,0.000002663839,0.000003353886,0.00008203179,0.000007390708,0.000402985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009844712,"threshold_uncertainty_score":0.003293335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005326283764169932,"score_gpt":0.2417670998554512,"score_spread":0.2364408160912813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}