{"id":"W2338409690","doi":"10.1038/ncomms11292","title":"Alternative splicing of MALT1 controls signalling and activation of CD4+ T cells","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Partenariat Canadien Contre Le Cancer; Silence Therapeutics; Deutsche Forschungsgemeinschaft","keywords":"Cell biology; Signalling; RNA splicing; Computational biology; Biology; Chemistry; Genetics; Gene; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008065712,0.00004857387,0.00007413528,0.00003194041,0.00003567233,0.000003099549,0.0001850128,0.00009274544,0.000006264999],"category_scores_gemma":[0.00009027252,0.00003686133,0.0000327995,0.00004264062,0.00009538593,0.000005171785,0.00008797608,0.00005419761,4.352734e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005049341,"about_ca_system_score_gemma":0.00002436893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008076646,"about_ca_topic_score_gemma":0.000009471724,"domain_scores_codex":[0.9996242,0.00005193994,0.0001341601,0.0000835518,0.0000585577,0.00004762414],"domain_scores_gemma":[0.9991847,0.00008045546,0.0001373964,0.0004190126,0.0001493599,0.00002909907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003564504,0.00003320293,0.002271242,0.000005610605,0.00002295387,1.787502e-8,0.00002378156,0.00003117086,0.9926093,0.003604932,0.00009952865,0.001262676],"study_design_scores_gemma":[0.0005934701,0.00004276237,0.008174323,0.00004701536,0.00001567024,4.165837e-7,0.00002903544,0.0003437238,0.9871523,0.0003772397,0.003162125,0.00006185872],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889961,0.00136247,0.007098708,0.001116598,0.00002559345,0.0001558948,0.00004230843,0.000004858395,0.001197446],"genre_scores_gemma":[0.9977345,0.0005334021,0.001480857,0.00009246133,0.00002030399,0.000005903684,0.00002597716,0.000005305877,0.0001012928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008738372,"threshold_uncertainty_score":0.1503161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127093505236974,"score_gpt":0.2843004616225666,"score_spread":0.2715911110988691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}