{"id":"W2338709534","doi":"10.1093/neuonc/nov215.21","title":"GENO-21BRCA1 PROTEIN EXPRESSION PREDICTS SURVIVAL IN GLIOBLASTOMA PATIENTS FROM A NRG ONCOLOGY/RTOG COHORT","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Temozolomide; Oncology; Medicine; Internal medicine; Hazard ratio; Proportional hazards model; PTEN; Tissue microarray; Survival analysis; Cohort; Biomarker; Glioblastoma; Radiation therapy; Immunohistochemistry; Cancer research; Biology; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002453538,0.0001629813,0.0002152936,0.0004732052,0.0002257381,0.00029141,0.000166038,0.0001614158,0.001048267],"category_scores_gemma":[0.000467912,0.0001036672,0.0001876025,0.0003282702,0.0001257444,0.0001306249,0.0002657398,0.0001819569,0.0002791196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002650756,"about_ca_system_score_gemma":0.0002351753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003747148,"about_ca_topic_score_gemma":0.006029926,"domain_scores_codex":[0.9999045,0.00001076048,0.000008482593,0.00003286992,0.00002000789,0.0000233172],"domain_scores_gemma":[0.99983,0.00001567223,0.00004836738,0.00001986844,0.00002596456,0.00005999656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002931455,0.00001849174,0.9956963,0.000005604523,0.00002945628,0.0001260454,0.00004196659,0.00005525202,0.001794745,0.00000831359,0.0002336518,0.00169701],"study_design_scores_gemma":[0.00001055423,0.00008120847,0.9986176,0.000002529365,0.00003258259,0.0004228832,0.00006057683,0.0001711921,0.0002189016,0.00001539382,0.0003647522,0.000001826368],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990718,0.00008320883,0.00004623903,0.0000182025,0.000002189066,0.000004821462,0.0005761044,0.000002678825,0.0001948142],"genre_scores_gemma":[0.9984809,0.00005864562,0.00005878975,0.0000141219,0.000003918867,0.000008346275,0.001253841,0.000002334772,0.0001191406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003747148,"threshold_uncertainty_score":0.00745064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02561541806796513,"score_gpt":0.2908054983070882,"score_spread":0.2651900802391231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}