{"id":"W2338792363","doi":"10.1093/neuonc/nov206.16","title":"ATCT-16CODEL (ALLIANCE-N0577; EORTC-26081/2208; NRG-1071; NCIC-CEC-2): PHASE III RANDOMIZED STUDY OF RT VS. RT + TMZ VS. TMZ FOR NEWLY DIAGNOSED 1p/19q-CODELETED ANAPLASTIC GLIOMA. ANALYSIS OF PATIENTS TREATED ON THE ORIGINAL PROTOCOL DESIGN","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre; Princess Margaret Cancer Centre; Toronto General Hospital","funders":"","keywords":"Medicine; Internal medicine; Clinical endpoint; Progression-free survival; Gastroenterology; Glioma; Phases of clinical research; Toxicity; Randomized controlled trial; Surgery; Oncology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001952777,0.001292039,0.001599378,0.0005055619,0.0002981918,0.0006544811,0.0009572255,0.001022396,0.005452706],"category_scores_gemma":[0.001546975,0.0004348997,0.0008672845,0.0006121527,0.0008856255,0.0004496597,0.0004621148,0.001634297,0.0009363104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001286394,"about_ca_system_score_gemma":0.002576574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001668561,"about_ca_topic_score_gemma":0.004372816,"domain_scores_codex":[0.9992678,0.0004803685,0.00003308195,0.00007595715,0.00006872026,0.00007401661],"domain_scores_gemma":[0.9990594,0.0001923677,0.0002439491,0.00006661944,0.00004746221,0.0003901753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9325466,0.01668495,0.002641046,0.001030523,0.0007633389,0.00009040368,0.00009010827,0.001398233,0.007242306,0.0003683036,0.004651786,0.03249245],"study_design_scores_gemma":[0.8986022,0.09330671,0.003550038,0.00003437256,0.000281649,0.00007938474,0.00001656688,0.0006735926,0.0008489278,0.0001832625,0.002409429,0.0000139434],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9585633,0.002579933,0.001590307,0.0008013874,0.0004600888,0.02428266,0.005032741,0.0002109947,0.006478678],"genre_scores_gemma":[0.9480222,0.002308183,0.004493337,0.001484392,0.0004698099,0.03046594,0.003924029,0.00007479687,0.008757241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005452706,"threshold_uncertainty_score":0.01824105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05897382743445861,"score_gpt":0.3590616237671926,"score_spread":0.300087796332734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}