{"id":"W2339109475","doi":"10.1038/srep22902","title":"Proinflammatory isoforms of IL-32 as novel and robust biomarkers for control failure in HIV-infected slow progressors","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Toronto General Hospital; St Joseph's Health Care; Lawson Health Research Institute; Hôpital Notre-Dame; Sunnybrook Health Science Centre; Centre hospitalier de l'Université Laval; Centre Hospitalier Universitaire de Sherbrooke; Health Sciences Centre; Ottawa Hospital; Capital District Health Authority; McGill University Health Centre; Maple Leaf Medical Clinic; HIV Legal Network; St. Paul's Hospital; Alberta Hip and Knee Clinic; St. Clair College; Université de Montréal; Institut National de la Recherche Scientifique; Université de Sherbrooke; Caprion (Canada); Clinique Paro Excellence; Centre Hospitalier de l’Université de Montréal","funders":"Styrelsen för Internationellt Utvecklingssamarbete; Pfizer","keywords":"Proinflammatory cytokine; Biomarker; Immunology; Medicine; CD8; Cohort; Viral load; Disease; Human immunodeficiency virus (HIV); Cytokine; Immune system; Inflammation; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008813202,0.0001337226,0.0002274835,0.0002707999,0.0001453377,0.00003203227,0.0000638154,0.000165791,0.0002604752],"category_scores_gemma":[0.0003847298,0.00008755764,0.00008550372,0.0001689204,0.0004106501,0.0002502718,0.00002908137,0.00008164249,0.000041624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004378711,"about_ca_system_score_gemma":0.0001073599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001666628,"about_ca_topic_score_gemma":0.00003118214,"domain_scores_codex":[0.9986398,0.00004089544,0.0005420359,0.0004431609,0.0000532484,0.0002808302],"domain_scores_gemma":[0.9989575,0.00008315392,0.0004072704,0.0003283342,0.0002012393,0.0000225547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003071922,0.0001174011,0.01457576,0.00003791882,0.00008346842,0.000006987704,0.0001421248,0.000005464871,0.9606155,0.0001023312,0.02146366,0.002542232],"study_design_scores_gemma":[0.005493002,0.0003258819,0.0154183,0.0003388467,0.00005987905,0.0008204319,0.000431789,0.00008423383,0.5728514,0.0004383472,0.4033754,0.0003625277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848039,0.0002310703,0.002294615,0.0004854777,0.01043845,0.001178495,0.00001044784,0.00006702005,0.0004906002],"genre_scores_gemma":[0.9794136,0.00000372785,0.0001686994,0.0000147803,0.00001185836,0.00009172481,0.00007460835,0.00001298596,0.02020798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3877641,"threshold_uncertainty_score":0.3570497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008165278126236858,"score_gpt":0.214742400210682,"score_spread":0.2065771220844452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}