{"id":"W2339175766","doi":"10.1101/gr.197897.115","title":"Impact of the X Chromosome and sex on regulatory variation","year":2016,"lang":"en","type":"article","venue":"Genome Research","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Air Force Office of Scientific Research; National Human Genome Research Institute; National Institute of Mental Health; National Defense Science and Engineering Graduate; National Institutes of Health; Edward Mallinckrodt, Jr. Foundation","keywords":"Biology; Autosome; Genetics; Expression quantitative trait loci; Quantitative trait locus; Genetic variation; X chromosome; Chromosome; Gene; Genome; Evolutionary biology; Single-nucleotide polymorphism; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003900383,0.00006188085,0.00007329179,0.000031743,0.00008501966,0.00001006208,0.000160519,0.00007551957,0.0001073936],"category_scores_gemma":[0.0001038872,0.00003082199,0.00006709677,0.00006532757,0.0002431848,0.000002275639,0.000136357,0.00005887095,0.00001075091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001856994,"about_ca_system_score_gemma":0.00008025967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001015526,"about_ca_topic_score_gemma":0.000002188177,"domain_scores_codex":[0.9991641,0.0001196908,0.0001288248,0.0001762989,0.000239918,0.000171148],"domain_scores_gemma":[0.9994586,0.00004881127,0.00003673337,0.0002984187,0.00009885279,0.00005856418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004555365,0.00006328153,0.008282142,0.00001225991,0.00003573206,5.255078e-7,0.00007305734,0.000003954573,0.981561,0.0005079148,0.0002014008,0.009213146],"study_design_scores_gemma":[0.0004626147,0.001131161,0.9080254,0.00002029604,0.000003209015,0.000006306754,0.00004801005,0.000003053154,0.08613879,0.001085978,0.002991945,0.00008323204],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972917,0.0001584186,0.00001637429,0.0002990461,0.00002370352,0.0001037786,0.00001819463,0.000002467947,0.002086268],"genre_scores_gemma":[0.9938491,0.0002064043,0.00001451441,0.00002704487,0.0001213729,0.000007377287,0.000002645112,0.000006772205,0.005764761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8997433,"threshold_uncertainty_score":0.1256884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03138082688305092,"score_gpt":0.3396256866333344,"score_spread":0.3082448597502834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}