{"id":"W2339235923","doi":"10.1021/acs.joc.5b01584","title":"Synthesis and Performance of a Biomimetic Indicator for Alkylating Agents","year":2015,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Safe Handling of Antineoplastic Drugs","field":"Health Professions","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Combinatorial chemistry; Biochemical engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00164534,0.00008038248,0.0002331937,0.00002653389,0.0001386101,0.00000265796,0.0002114165,0.00007842403,0.0001772509],"category_scores_gemma":[0.0022359,0.00005211667,0.00003363668,0.00008640157,0.00006869237,0.00004345061,0.00007422471,0.0002505083,0.000006885202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004750116,"about_ca_system_score_gemma":0.0005960066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002873189,"about_ca_topic_score_gemma":3.347503e-7,"domain_scores_codex":[0.9990091,0.00005460187,0.0005113706,0.00005587436,0.0001990715,0.0001699636],"domain_scores_gemma":[0.9974029,0.001336927,0.0008161235,0.0001347853,0.0001994132,0.0001098621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001668546,0.0001625064,0.1826059,0.002825398,0.0003733434,0.000004766483,0.0145048,0.00001260144,0.7863942,0.000005044749,0.007073053,0.004369809],"study_design_scores_gemma":[0.004274723,0.0003153205,0.02404123,0.002248611,0.0006786723,0.0002593515,0.0125,0.00123468,0.9527332,0.0001627726,0.001286612,0.000264797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985773,0.0002426581,0.000187928,0.0004060054,0.0001525273,0.00009665825,0.000004684003,0.000005945183,0.0003263159],"genre_scores_gemma":[0.9986734,0.00006631226,0.0008076997,0.00004581448,0.0002268039,0.000001904309,3.714365e-7,0.00001632786,0.0001613776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.166339,"threshold_uncertainty_score":0.2676743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05370384879427556,"score_gpt":0.3484744704854715,"score_spread":0.2947706216911959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}