{"id":"W2339286673","doi":"10.1152/ajplung.00065.2016","title":"Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo","year":2016,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Downregulation and upregulation; Lung; Myofibroblast; Transforming growth factor; Extracellular matrix; Cell biology; Parenchyma; Chemistry; Pulmonary surfactant; Transforming growth factor beta; Pathology; Biology; Endocrinology; Fibrosis; Internal medicine; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004334021,0.0002492454,0.0009486008,0.0003786499,0.00006270615,0.000003854439,0.0001470151,0.0001299736,0.00006097091],"category_scores_gemma":[0.0002651811,0.0001671328,0.0001864869,0.000279608,0.0005304632,0.0001342343,0.000133638,0.000424649,0.000001736329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001564386,"about_ca_system_score_gemma":0.0002858098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005889697,"about_ca_topic_score_gemma":0.00000120026,"domain_scores_codex":[0.9973937,0.000537847,0.0007979152,0.0004144948,0.0003277507,0.0005283278],"domain_scores_gemma":[0.998197,0.0002202945,0.0006787781,0.0003506867,0.000293728,0.0002595512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003583754,0.0001339308,0.001223657,0.0007090954,0.0001010907,0.00004786355,0.0001137798,0.0001663595,0.9909137,0.0000320781,0.00001105725,0.002963604],"study_design_scores_gemma":[0.002848357,0.002180645,0.04379663,0.001281694,0.0000613022,0.000128619,0.0001602926,0.0007709525,0.9482596,0.0002471104,0.00007678729,0.0001879936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967631,0.002028178,0.0004882289,0.0002020413,0.00009707674,0.0003677878,0.000006031788,0.00001128275,0.00003630147],"genre_scores_gemma":[0.9983776,0.0007811935,0.000544481,0.0001139297,0.0001066376,0.000008541743,0.000002710283,0.00003850857,0.00002644215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04265411,"threshold_uncertainty_score":0.6815479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009967436658772996,"score_gpt":0.2908618360444137,"score_spread":0.2808943993856407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}