{"id":"W2339509426","doi":"10.1002/jbmr.2852","title":"Vascular Calcification Induced by Chronic Kidney Disease Is Mediated by an Increase of 1α-Hydroxylase Expression in Vascular Smooth Muscle Cells","year":2016,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Universitat de Lleida; Fundación para el Fomento en Asturias de la Investigación Científica Aplicada y la Tecnología","keywords":"Calcitriol; Internal medicine; Endocrinology; Vascular smooth muscle; Kidney; Uremia; Kidney disease; Calcium; Calcification; Hyperphosphatemia; Parathyroid hormone; Chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000200696,0.0003404587,0.0002969279,0.0004299769,0.0002369174,0.0002689768,0.0001158823,0.0002727763,0.001014608],"category_scores_gemma":[0.000113056,0.0001937785,0.0003832258,0.0002486984,0.0002796894,0.0001459445,0.000213731,0.0005269226,0.0001818525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001926077,"about_ca_system_score_gemma":0.0001139597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005805848,"about_ca_topic_score_gemma":0.0007052607,"domain_scores_codex":[0.999772,0.00003566129,0.00001808712,0.00004681441,0.00007577728,0.00005156131],"domain_scores_gemma":[0.9997768,0.00002183689,0.00007544558,0.00002569167,0.00003083245,0.00006935257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001110519,0.00002285406,0.001194746,0.00002984885,0.000006907424,0.00008457017,0.00001608779,0.00000670415,0.997884,0.00002217696,0.0000171282,0.0006038355],"study_design_scores_gemma":[0.00006430068,0.001160453,0.1997654,0.00002455354,0.00006729591,0.001319316,0.0001631948,0.0005113296,0.794437,0.0001689244,0.002306334,0.00001187865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939139,0.003859602,0.001164927,0.00009294994,0.00004458652,0.00001407401,0.0001349898,0.00004142008,0.000733538],"genre_scores_gemma":[0.9966819,0.001248781,0.0006043332,0.00003169247,0.00003341472,0.00002236292,0.0001401421,0.00000397254,0.00123339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001014608,"threshold_uncertainty_score":0.003394246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02960319242071706,"score_gpt":0.333929265354601,"score_spread":0.304326072933884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}