{"id":"W2339639032","doi":"10.1038/srep23820","title":"Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"Directorate for Biological Sciences; Singapore Millennium Foundation; Swedish Cancer Foundation","keywords":"Aryl hydrocarbon receptor; Biology; Intestinal epithelium; Cell biology; CD11c; Intestinal mucosa; Immunology; Interleukin 22; Transcription factor; Ex vivo; In vivo; Epithelium; Interleukin; Cytokine; Internal medicine; Medicine; Phenotype; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002030771,0.0001835469,0.0001828181,0.0001787076,0.0005536911,0.00008864977,0.0001496389,0.0001025965,0.0007425424],"category_scores_gemma":[0.0006626932,0.0001062328,0.00005075315,0.0002339346,0.0004606049,0.0001988276,0.0001614469,0.0003490119,0.0003787855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001180888,"about_ca_system_score_gemma":0.0001408204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001247509,"about_ca_topic_score_gemma":0.00004878419,"domain_scores_codex":[0.9982296,0.0001689757,0.0006497945,0.0005130692,0.00008164199,0.0003569822],"domain_scores_gemma":[0.9987552,0.0002982371,0.0003265096,0.0004674551,0.0001247673,0.00002784962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005604239,0.00006449696,0.007074627,0.000007969674,0.00001715071,0.00001730404,0.001108524,0.000001518533,0.9680346,0.00002343743,0.007368081,0.0162263],"study_design_scores_gemma":[0.0003162469,0.00006759572,0.007386849,0.0002784562,0.000009812844,0.000931107,0.0007101719,0.00001830429,0.8002558,0.0002659453,0.1895467,0.0002129084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804044,0.0004397057,0.0002120095,0.0004119705,0.01652861,0.0002236959,2.562579e-7,0.00008456465,0.001694732],"genre_scores_gemma":[0.9746647,0.00001061655,0.0002308137,0.00006083033,0.00002895925,0.00002543541,0.00001997877,0.00001574532,0.02494293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1821787,"threshold_uncertainty_score":0.8130318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01302891986823207,"score_gpt":0.2157306021759367,"score_spread":0.2027016823077047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}