{"id":"W2339725236","doi":"10.1177/0748233716638004","title":"The protective effects of insulin-like growth factor-1 on neurochemical phenotypes of dorsal root ganglion neurons with BDE-209-induced neurotoxicity <i>in vitro</i>","year":2016,"lang":"en","type":"article","venue":"Toxicology and Industrial Health","topic":"Biochemical effects in animals","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Neurotoxicity; Neuroprotection; Dorsal root ganglion; PI3K/AKT/mTOR pathway; Protein kinase B; LY294002; Oxidative stress; Chemistry; Cell biology; Neurite; Pharmacology; Signal transduction; Biology; Biochemistry; Neuroscience; Toxicity; In vitro; Sensory system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004284062,0.0002453804,0.0006871974,0.0001130332,0.00009118914,0.000004075058,0.0001443722,0.0004476063,0.000004749917],"category_scores_gemma":[0.00202178,0.0001325085,0.00006089672,0.0003102178,0.0004991033,0.00004322516,0.00007414784,0.0008948531,0.000001600104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001110241,"about_ca_system_score_gemma":0.0003900336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008671588,"about_ca_topic_score_gemma":0.00001841325,"domain_scores_codex":[0.9976825,0.0006787805,0.0004927398,0.0004311916,0.0002602689,0.0004544796],"domain_scores_gemma":[0.9966881,0.002422209,0.0003395752,0.0002737215,0.00008304558,0.0001933341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01603689,0.00054283,0.00151781,0.0001965667,0.00003339544,0.00001857932,0.00008985962,1.221756e-7,0.9627911,0.0002946372,0.0001086725,0.01836948],"study_design_scores_gemma":[0.006949498,0.01506142,0.03102663,0.0003384553,0.00002554721,0.00002619294,0.000008671663,0.00000697514,0.9462512,0.0001282706,0.00006202568,0.0001151603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931185,0.0001018709,0.00002135469,0.003931664,0.0002634019,0.002426625,0.00001766915,0.00003176142,0.00008720801],"genre_scores_gemma":[0.9988075,0.00004111368,0.00002102016,0.0008611961,0.0001510452,0.0000795415,0.000001867268,0.00002548207,0.00001118788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02950882,"threshold_uncertainty_score":0.5403541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02456181534573963,"score_gpt":0.2822087923124176,"score_spread":0.2576469769666779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}